临床神经外科杂志2019，Vol.16Issue(4)：309-314,6.DOI:10.3969/j.issn.1672-7770.2019.04.007
中国大陆人群脑卒中后癫痫发生率的Meta分析
Meta-analysis of incidence of post-stroke epilepsy in Chinese population
摘要
Abstract
To evaluate the incidence of post-stroke epilepsy in Chinese population by Meta-analysis.Methods The CNKI, Wanfang, Chongqing VIP network , PubMed, EMbase and Wiley database were searched to identify observational studies of post-stroke seizures from January 2010 to June 2018.The data were analyzed by Meta-analysis with Stata 11.0 software.Results 36 articles involving 50 748 stroke patients and 3 913 post-stroke epilepsy patients were included. Meta-analysis showed the incidence of post-stroke epilepsy was 7.5%(95% CI:6.8%-8.2%). Subgroup analysis showed that the incidence of early post-stroke epilepsy was higher than that of late epilepsy (4.7% vs 2.7%, P ＜0.01).The incidence of male post-stroke epilepsy was slightly higher than that of female (7.8% vs 7.3%, P＜0.01).The incidence of epilepsy after cerebral infarction, cerebral hemorrhage and subarachnoid hemorrhage were 6.2%, 9.0% and 15.5%respectively(P＜0.01).Conclusions The incidence of post-stroke epilepsy in Chinese is 7.5%. The incidence of post-stroke epilepsy is related to gender and stroke type.Male and cerebral hemorrhage may be the risk factors of post-stroke epilepsy.关键词
脑卒中/癫痫/发生率/Meta分析Key words
stroke/epilepsy/incidence/Meta-analysis分类
医药卫生引用本文复制引用
李倩,谢琛,刘静茹,韩红,侯丽敏,赵志芳..中国大陆人群脑卒中后癫痫发生率的Meta分析[J].临床神经外科杂志,2019,16(4):309-314,6.基金项目
河北省邢台市科技支撑计划项目(2017ZC063) （2017ZC063）
