肿瘤预防与治疗2019，Vol.32Issue(7)：594-600,7.
声门癌术后复发危险因素分析
Risk Factors Related to Recurrence of Glottic Carcinoma After Surgery
摘要
Abstract
Objective: To analyze the related factors of postoperative recurrence of glottic laryngeal carcinoma, and pro-vide basis for the treatment of laryngeal carcinoma. Methods: Retrospective analysis of 172 patients with glottic carcinoma were treated for the first time in our otolaryngology, head and neck surgery department from January 2013 to March 2018. Different surgical methods were selected according to the extent of the lesion. Surgical methods, TNM stage, pathological dif-ferentiation, type of surgery, whether precommissure was invaded, and postoperative recurrence were analyzed. Results:Postoperative recurrence occurred in 21 patients, with a recurrence rate of 12. 21% . T1b stage had the highest recurrence rate of 20. 0% (9／45), and there was no significant difference in the recurrence rate among different stages (P>0. 05). Whether precommissure was involved, surgical margin pathology and different degrees of pathological differentiation affected the postoperative recurrence rate, and the differences were significant (P <0. 05). There was no statistically significant difference in the recurrence rate between groups with different TNM stages, surgical methods and depths of tumor invasion (P>0. 05). Multi-factor Logistics regression analysis results showed that there was no correlation between tumor infiltration depth and tumor recurrence rate ( P >0. 05), while TNM stage, surgical method, whether preassociation was involved, surgical margin pathology and postoperative pathological type were risk factors for tumor recurrence (P<0. 05). Conclu-sion: Whether preassociation was involved, surgical margin pathology, postoperative pathology were independent risk factors for recurrence of laryngeal cancer, while TNM stage, surgical method were risk factors for tumor recurrence.关键词
声门癌/术后复发率/危险因素Key words
Glottic carcinoma/Postoperative recurrence rate/Risk factors分类
医药卫生引用本文复制引用
赵谦,赵瑞敏,姚小宝,李宏慧,刘俊松,许崇文..声门癌术后复发危险因素分析[J].肿瘤预防与治疗,2019,32(7):594-600,7.基金项目
陕西省科技技术研究发展计划项目(编号:2016SF-203) （编号:2016SF-203）
陕西省自然科学基础研究计划面上项目(编号:2017JM8072) This study was supported by Science Technology Development and Research Project of Shaanxi ( NO. 2016SF-203) and Natural Science Basic Research Project (NO. 2017JM8072) . （编号:2017JM8072）
