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斑马鱼模型在心血管疾病中药筛选和机制研究中的应用

赵慧 樊华 周端 王佑华

中国中医药信息杂志2018,Vol.25Issue(9):133-137,5.
中国中医药信息杂志2018,Vol.25Issue(9):133-137,5.DOI:10.3969/j.issn.1005-5304.2018.09.033

斑马鱼模型在心血管疾病中药筛选和机制研究中的应用

Application of Zebrafish Model in TCM Screening in Cardiovascular Diseases and Mechanism Research

赵慧 1樊华 1周端 1王佑华1

作者信息

  • 1. 上海中医药大学附属龙华医院 上海 200032
  • 折叠

摘要

Abstract

Zebrafish is one of the important model vertebrates in the study of life science at present. It has similar physiological and biochemical characteristics to mammals, and has the advantages of high efficiency, rapidness and largescale. TCM has complex active ingredients and various targets, so the application of zebrafish model in TCM research is increasingly wide. This article reviewed the application status of zebrafish model in TCM screening cardiovascular diseases and mechanism research from the aspects of angiogenesis, myocardial injury, hyperlipidemia, and cardiovascular toxicity.

关键词

斑马鱼/心血管/中药/筛选/机制/综述

Key words

zebrafish/cardiovascular/TCM/screening/mechanism/review

分类

医药卫生

引用本文复制引用

赵慧,樊华,周端,王佑华..斑马鱼模型在心血管疾病中药筛选和机制研究中的应用[J].中国中医药信息杂志,2018,25(9):133-137,5.

基金项目

国家自然科学基金(81328025) (81328025)

上海市科委科研计划项目(15401902500 ()

17401901600) ()

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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