中国中医药信息杂志2018,Vol.25Issue(9):133-137,5.DOI:10.3969/j.issn.1005-5304.2018.09.033
斑马鱼模型在心血管疾病中药筛选和机制研究中的应用
Application of Zebrafish Model in TCM Screening in Cardiovascular Diseases and Mechanism Research
摘要
Abstract
Zebrafish is one of the important model vertebrates in the study of life science at present. It has similar physiological and biochemical characteristics to mammals, and has the advantages of high efficiency, rapidness and largescale. TCM has complex active ingredients and various targets, so the application of zebrafish model in TCM research is increasingly wide. This article reviewed the application status of zebrafish model in TCM screening cardiovascular diseases and mechanism research from the aspects of angiogenesis, myocardial injury, hyperlipidemia, and cardiovascular toxicity.关键词
斑马鱼/心血管/中药/筛选/机制/综述Key words
zebrafish/cardiovascular/TCM/screening/mechanism/review分类
医药卫生引用本文复制引用
赵慧,樊华,周端,王佑华..斑马鱼模型在心血管疾病中药筛选和机制研究中的应用[J].中国中医药信息杂志,2018,25(9):133-137,5.基金项目
国家自然科学基金(81328025) (81328025)
上海市科委科研计划项目(15401902500 ()
17401901600) ()