中国卒中杂志2019，Vol.14Issue(6)：527-532,6.DOI:10.3969/j.issn.1673-5765.2019.06.003
基于磁敏感加权成像的pc-ASPECTS评分对后循环急性缺血性卒中预后的预测价值
Predictive Value of pc-ASPECTS Based on Susceptibility Weighted Imaging for Prognosis of Patients with Posterior Circulation Acute Ischemic Stroke
张盼盼 1刘远洪 1闫斌 1刘素梅 1葛晓航 1牛智领 1刘乐喜 1聂志余2
作者信息
- 1. 457000 濮阳濮阳市人民医院神经内科
- 2. 同济大学附属同济医院神经内科
- 折叠
摘要
Abstract
Objective To assess the value of posterior circulation ASPECTS (pc-ASPECTS) based on SWI in predicting the clinical outcome of patients with posterior circulation acute ischemic stroke (AIS). Methods The clinical and imaging data of posterior circulation AIS patients who were not treated with endovascular recanalization and intravenous or intra-arterial alteplase were analyzed. The prognosis at 3 months after symptom onset was assessed by mRS, good prognosis was defined as mRS 0-2, and poor prognosis was defined as mRS 3-6. Multivariate logistic regression analysis was used to determine the independent predictors of clinical outcome. The area under the receiver operating characteristic (ROC) curve was used to evaluate the predictive value of the pc-ASPECTS based on SWI for the prognosis of patients with posterior circulation AIS. Results A total of 63 patients with posterior circulation AIS were included in the study, 42 (66.7%) patients had a good prognosis, and 21 (66.7%) patients had a poor prognosis. The univariate analysis showed that there was significant difference in the NIHSS on admission (P<0.001) and pc-ASPECTS (P<0.001) between good and poor prognosis groups. The multivariate logistic regression analysis showed that the pc-ASPECTS≥6 could independently predict favorable outcome in posterior circulation AIS patients ( OR 2.03; 95% CI 1.04-3.95, P=0.039). ROC analysis indicated that the area under the ROC curve of the pc-ASPECTS based on SWI was 0.80 (95% CI 0.69-0.91). Conclusions The pc-ASPECTS based on SWI can independently predict clinical outcome at 3 months after symptom onset in patients with posterior circulation AIS.关键词
磁敏感加权成像/后循环/缺血性卒中/预后/受试者工作特征曲线Key words
Susceptibility weighted imaging/Posterior circulation/Ischemic stroke/Outcome/Receiver operating characteristic curve引用本文复制引用
张盼盼,刘远洪,闫斌,刘素梅,葛晓航,牛智领,刘乐喜,聂志余..基于磁敏感加权成像的pc-ASPECTS评分对后循环急性缺血性卒中预后的预测价值[J].中国卒中杂志,2019,14(6):527-532,6.
