浙江医学2018，Vol.40Issue(16)：1830-1832,3.DOI:10.12056/j.issn.1006-2785.2018.40.16.2017-2039
触珠蛋白在小儿上呼吸道感染诊断中的临床意义
Serum levels of haptoglobin in children with upper respiratory tract infection and its clinical significance
赵昕峰 1吴亦栋 1陈刚 1高扬 1张利华1
作者信息
摘要
Abstract
Objective To investigate the serum levels of haptoglobin (Hp) in children with upper respiratory tract infection (URTI) and its clinical significance. Methods Two hundred and four children with URTI and 100 healthy children (control group) were enrolled. Serum levels of Hp and C- reactive protein (CRP) and white blood cell count (WBC) were measured in all subjects. Results Serum levels of Hp and CRP, and WBC in URTI group were significantly higher than those in healthy control group(all P＜0.01). The levels of Hp were correlated with CRP and WBC in URTI group. The area under the ROC curve(AUC) of Hp (0.853) was higher than that of CRP (0.834) and WBC (0.633) for diagnosing URTI. When the cutoff value of Hp was set at 66.3μg/ml, its sensitivity and specificity was 0.887 and 0.540 for diagnosis of URTI. Conclusion Serum haptoglobin level might serve as a new reference index for diagnosis of URTI in children.关键词
触珠蛋白/上呼吸道感染/C反应蛋白/白细胞计数Key words
Haptoglobin/Upper respiratory tract infection/C reactive protein/Whiteblood cell count引用本文复制引用
赵昕峰,吴亦栋,陈刚,高扬,张利华..触珠蛋白在小儿上呼吸道感染诊断中的临床意义[J].浙江医学,2018,40(16):1830-1832,3.
