肿瘤防治研究2018，Vol.45Issue(3)：160-162,3.DOI:10.3971/j.issn.1000-8578.2018.17.0804
剂量体积联合等效均匀剂量优化在鼻咽癌调强放疗危及器官优化中的应用
Application of Dose-volume Combined with Equivalent Uniform Dose Optimization in Optimization of OAR in IMRT on Nasopharyngeal Carcinoma
庞皓文 1孙小杨 1杨波1
作者信息
- 1. 西南医科大学附属医院肿瘤科放疗室 646000 泸州
- 折叠
摘要
Abstract
Objective To investigate the application of dose-volume (DV) combined with equivalent uniform dose (EUD) in the optimization of organ at risk (OAR) in IMRT on nasopharyngeal carcinoma. Methods We selected 55 patients with nasopharyngeal carcinoma who received IMRT planning in the Department of Oncology, The Affiliated Hospital of Southwest Medical University. The optimization methods were divided into conventional DV optimization and DV and EUD combined optimization. The dosages of the target and OAR after two optimization methods were evaluated. Results There was no significant difference in the prescription dose, homogeneity index or conformity index between the two groups (all P＞0.05). We found that the mean OAR doses for DV and EUD combined optimization were significantly lower than those for conventional DV optimization (all P＜0.001). Conclusion DV and EUD combined optimization is successfully applied to the optimization of OAR in IMRT on nasopharyngeal carcinoma, and we give an evaluation methods for the dosimetry of organs at risk in IMRT, in order to reduce the influence of subjective factors.关键词
剂量体积优化/等效均匀剂量优化/调强放疗/鼻咽癌Key words
Dose-volume optimization/Equivalent uniform dose optimization/IMRT/Nasopharyngeal carcinoma (NPC)分类
医药卫生引用本文复制引用
庞皓文,孙小杨,杨波..剂量体积联合等效均匀剂量优化在鼻咽癌调强放疗危及器官优化中的应用[J].肿瘤防治研究,2018,45(3):160-162,3.
