肿瘤防治研究2018，Vol.45Issue(3)：171-174,4.DOI:10.3971/j.issn.1000-8578.2018.17.0814
癌症基因组图集数据库及其应用
The Cancer Genome Atlas Database and Its Application
孙继政 1唐瑜菁 1洒荣波 1高艳霞1
作者信息
- 1. 泰山医学院生命科学学院 271016 泰安
- 折叠
摘要
Abstract
Cancer is uncontrolled growth of cells that caused by DNA variations. Identifying the variations and their interactions in each cancer's genome will accelerate the understanding of the molecular basis of cancer. This work will improve our abilities of cancer prevention, early detection and treatment. So, American National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI) initiated. The Cancer Genome Atlas (TCGA) project. Unprecedented amount of data was generated in the process. We can learn more about the molecular basis of cancer by analyzing the data from TCGA, to lay the foundation for precision therapy and personalized cancer care. In this paper, we introduced the development of data, data types and levels, retrieval and application, and benefits of TCGA in detail. Our introductions aim to help researchers learn and use the dataset to develop more effective ways to diagnose, treat and prevent cancer.关键词
癌症基因组图集计划/数据库/数据类型/数据获取与应用Key words
The Cancer Genome Atlas (TCGA) Project/Database/Data types/Retrieval and application of data分类
医药卫生引用本文复制引用
孙继政,唐瑜菁,洒荣波,高艳霞..癌症基因组图集数据库及其应用[J].肿瘤防治研究,2018,45(3):171-174,4.
