肿瘤药学2019,Vol.9Issue(3):354-358,370,6.DOI:10.3969/j.issn.2095-1264.2019.03.01
miRNA与其宿主同源基因lncRNA在肿瘤发生发展中的研究进展★
The Advance Research of miRNAs and Host Homologous Gene lncRNAs in Cancer Tumorigenesis★
摘要
Abstract
Recently, more and more studies found that some miRNA genes were located within the intronic regions of lncRNAs which were called "host homologous genes of the miRNAs". miRNAs can be transcribed along with the transcription of host homologous gene lncRNAs. Due to the specific locations of those miRNAs, some researchers consider it that the miRNAs could be co-expressed with the corresponding lncRNAs, and they may play the similar roles in cancer tumorigenesis. This review aims to summarize the roles of miRNA and host homologous gene lncRNAs in the development of cancer tumorigenesis, providing new ideas for subsequent anti-tumor research.关键词
微小RNA/长链非编码 RNA/宿主同源基因/肿瘤发生发展Key words
miRNA/lncRNA/Host homologous gene/Tumorigenesis分类
医药卫生引用本文复制引用
胡晓云,刘明妍,吴慧哲,魏敏杰,何苗..miRNA与其宿主同源基因lncRNA在肿瘤发生发展中的研究进展★[J].肿瘤药学,2019,9(3):354-358,370,6.基金项目
国家自然科学基金面上项目(81673475,81872905) (81673475,81872905)
辽宁省科技计划(2014226033) (2014226033)
沈阳市科技计划项目重点实验室专项(F16-094-1-00). (F16-094-1-00)