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miRNA与其宿主同源基因lncRNA在肿瘤发生发展中的研究进展★

胡晓云 刘明妍 吴慧哲 魏敏杰 何苗

肿瘤药学2019,Vol.9Issue(3):354-358,370,6.
肿瘤药学2019,Vol.9Issue(3):354-358,370,6.DOI:10.3969/j.issn.2095-1264.2019.03.01

miRNA与其宿主同源基因lncRNA在肿瘤发生发展中的研究进展★

The Advance Research of miRNAs and Host Homologous Gene lncRNAs in Cancer Tumorigenesis★

胡晓云 1刘明妍 1吴慧哲 1魏敏杰 1何苗1

作者信息

  • 1. 中国医科大学药学院药理教研室/辽宁省分子靶向抗肿瘤药物药理学研究与评价重点实验室,辽宁 沈阳,110122
  • 折叠

摘要

Abstract

Recently, more and more studies found that some miRNA genes were located within the intronic regions of lncRNAs which were called "host homologous genes of the miRNAs". miRNAs can be transcribed along with the transcription of host homologous gene lncRNAs. Due to the specific locations of those miRNAs, some researchers consider it that the miRNAs could be co-expressed with the corresponding lncRNAs, and they may play the similar roles in cancer tumorigenesis. This review aims to summarize the roles of miRNA and host homologous gene lncRNAs in the development of cancer tumorigenesis, providing new ideas for subsequent anti-tumor research.

关键词

微小RNA/长链非编码 RNA/宿主同源基因/肿瘤发生发展

Key words

miRNA/lncRNA/Host homologous gene/Tumorigenesis

分类

医药卫生

引用本文复制引用

胡晓云,刘明妍,吴慧哲,魏敏杰,何苗..miRNA与其宿主同源基因lncRNA在肿瘤发生发展中的研究进展★[J].肿瘤药学,2019,9(3):354-358,370,6.

基金项目

国家自然科学基金面上项目(81673475,81872905) (81673475,81872905)

辽宁省科技计划(2014226033) (2014226033)

沈阳市科技计划项目重点实验室专项(F16-094-1-00). (F16-094-1-00)

肿瘤药学

OACSTPCD

2095-1264

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