肿瘤药学2019，Vol.9Issue(3)：376-379,4.DOI:10.3969/j.issn.2095-1264.2019.03.05
斑马鱼在消化道肿瘤中的应用研究进展
Research Advances in the Application of Zebrafish in Study of Gastrointestinal Carcinomas
冀慧红 1刘俊2
作者信息
- 1. 山西医科大学,山西 太原,030001
- 2. 山西医科大学附属人民医院感染性疾病科,山西 太原,030012
- 折叠
摘要
Abstract
It is of great significance to understand the specific molecular mechanism of the gastrointestinal carcinoma for its prevention and treatment. Zebrafish, as a unique living vertebrate model, has highly conserved genes with human. Its transparent early embryo is con-ducive to the real-time observation of the developing process. Since the carcinogenesis of zebrafish organs and tissues is very similar to that of humans, zebrafish become a preferable cancer model for the in vivo research of gastrointestinal carcinomas development, the development and screening of anti-tumor drugs and the determination of the best treatment options. These zebrafish cancer models include hepatocellular carcinoma, colorectal cancer, pancreatic cancer and gastric cancer. In this review summarized was the application progress of gastrointesti-nal carcinomas models by zebrafish.关键词
斑马鱼/消化道肿瘤/药物筛选/肿瘤模型Key words
Zebrafish/Gastrointestinal carcinomas/Drug screening/Cancer model分类
医药卫生引用本文复制引用
冀慧红,刘俊..斑马鱼在消化道肿瘤中的应用研究进展[J].肿瘤药学,2019,9(3):376-379,4.
