中国耳鼻咽喉头颈外科2018，Vol.25Issue(7)：349-352,4.DOI:10.16066/j.1672-7002.2018.07.002
头颈部获得性免疫缺陷综合征相关性卡波西肉瘤临床分析
Clinical analysis of AIDS-related Kaposi's sarcoma in head and neck
侯静 1房高丽 1张立松 1孙挥宇 1王成硕2
作者信息
- 1. 首都医科大学附属北京地坛医院耳鼻咽喉科, 北京 100102
- 2. 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科, 耳鼻咽喉头颈科学教育部重点实验室(首都医科大学), 北京 100730
- 折叠
摘要
Abstract
OBJECTIVE To summarize the clinical features of the acquired immunodeficiency syndrome-related Kaposi's sarcoma(AIDS-KS) in head and neck. METHODS The clinical data of 20 inpatients with AIDS-KS in head and neck from June 2009 to September 2016 in Beijing Ditan Hospital were retrospectively analyzed. RESULTS All 20 patients were male, median age 38.50±10.98. One case was Manchu, 1 case was of Uygur, and others were Han nationality. There were 7 cases with homosexuality history, 2 cases with blood transfusion history, and 1 case with prostitution history. Mass in head and face was the first symptom in 10 cases. The head and neck skin and mucosa were involved, including 2 cases with nasal mucosa involvement, 4 cases with auricle skin involvement, 8 cases with oral mucosal involvement, 3 cases with facial skin involvement, 1 case with neck skin involvement, 1 case with eyelid conjunctiva involvement. Four cases had disseminated lesions. When diagnosed, the CD4+T lymphocyte were 52.55±47.87/mm3. The CD4+T were less than 200/mm3 in all of the patients, including CD4+T＜50/mm3 in 15 cases(75％). After treatment with highly active antiretroviral therapy combined with or without chemotherapy, 12 cases were discharged. Eight cases died due to respiratory failure or septic shock or other reasons. CONCLUSION Kaposi's sarcoma of the head and neck might be the first visit of AIDS patients. Some of the patients get partial remission after highly active antiretroviral therapy and the overall prognosis is poor.关键词
获得性免疫缺陷综合征/肉瘤/卡波西/头颈部肿瘤Key words
Acquired Immunodeficiency Syndrome/Sarcoma/Kaposi/Head and Neck Neoplasms引用本文复制引用
侯静,房高丽,张立松,孙挥宇,王成硕..头颈部获得性免疫缺陷综合征相关性卡波西肉瘤临床分析[J].中国耳鼻咽喉头颈外科,2018,25(7):349-352,4.
