国际老年医学杂志2019,Vol.40Issue(4):207-210,4.DOI:10.3969/j.issn.1674-7593.2019.04.006
Ⅲa期非小细胞肺癌根治性放疗或联合化疗的疗效比较∗
Therapeutic Effects in Patients with Stage IIIa Non-small Cell Lung Cancer after Radical Radiotherapy or Radiotherapy Combined with Chemotherapy
摘要
Abstract
Objective To analyze the prognosis and influencing factors in patients with stage Ⅲa non -small cell lung cancer (NSCLC) after radical radiotherapy or radiotherapy combined with chemotherapy. Methods 112 patients with stage IIIa NSCLC in our hospital between September 2014 and February 2017 were divided into two groups. 39 cases in the control group were given radical radiotherapy. 73 cases in the observation group were given radical radiotherapy combined with chemotherapy. The thera-peutic effects and influencing factors were compared between the two groups. Results The rate of complete remission (CR) and the overall response rate in the observation group were significantly higher than those in the control group (P<0.05). One-year survival rate, two-year survival rate and five-year survival rate in the observation group were significantly higher than those in the control group (P<0.05). One-year mortality rate, two-year mortality rate and five-year mortality rate in the observation group were lower than those in the control group (P<0.05). N-grade, radiotherapy and themotherapy were independent prognostic factors af-fecting actual survival rate, recurrence-free survival rate and metastasis-free survival rate. Conclusion The survival, therapeutic effects and prognosis are better in stage IIIa NSCLC patients treated with radical radiotherapy combined with concurrent chemotherapy than those treated with radical radiotherapy alone.关键词
Ⅲa期/非小细胞肺癌/放疗/化疗/生存率Key words
Stage Ⅲa/Non-small cell lung cancer/Radiotherapy/Chemotherapy/Survival rate引用本文复制引用
吴阔..Ⅲa期非小细胞肺癌根治性放疗或联合化疗的疗效比较∗[J].国际老年医学杂志,2019,40(4):207-210,4.基金项目
邢台市科学技术研究与发展指导计划项目 (201032029) (201032029)