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舟山地区蝙蝠轮状病毒分子鉴定和分析∗

HE Ting ZHU Chang-Qiang AI Le-Le HU Dan LYU Rui-Chen TAN Wei-Long WANG Chang-Jun QIAN Hui1

寄生虫与医学昆虫学报2019,Vol.26Issue(1):22-29,8.
寄生虫与医学昆虫学报2019,Vol.26Issue(1):22-29,8.DOI:10.3969/j.issn.1005-0507.2019.01.004

舟山地区蝙蝠轮状病毒分子鉴定和分析∗

IDENTIFICATION AND ANALYSIS OF BAT ROTAVIRUS IN ZHOUSHAN AREAS

HE Ting 1ZHU Chang-Qiang 2AI Le-Le 2HU Dan 2LYU Rui-Chen 2TAN Wei-Long 2WANG Chang-Jun 1QIAN Hui12

作者信息

  • 1. School of Medicine, Jiangsu University, Zhenjiang 212000, China
  • 2. Center for Disease Control and Prevention of Eastern Command , Nanjing 210000, China
  • 折叠

摘要

Abstract

The prevalence of rotavirus in bat populations were screened with primer sets targeting VP segments of rotavirus in Zhoushan areas, Zhejiang Province, south-east littoral of China, from 2015 to 2018. The positive rate of rotavirus in bat Rhinolophus pusillus varied from 6.15% (4/65) in 2015, 2.08% (1/48) in 2016, 2.86% (2/70) in 2017 and 0 (0/101) in 2018. The VP7 sequence detected was closely related to bat-derived rotavirus, showing 96% nt autoploidy; the detected VP3 sequence shared 90% autoploidy with the rotavirus infected in human; the detected VP6 sequence had 95% autoploidy with the cat-derived rotavirus. Although the full length of rotavirus was not obtained, we can also speculate that the rotavirus carried by R. pusillus in Zhoushan areas might be a recombinant strain with great potential to spread across-kingdoms to humans. This study might play an important role of monitoring and warning this virus.

关键词

蝙蝠/轮状病毒/进化分析

Key words

Bat/Rotavirus/Phylogenetic analysis

引用本文复制引用

HE Ting,ZHU Chang-Qiang,AI Le-Le,HU Dan,LYU Rui-Chen,TAN Wei-Long,WANG Chang-Jun,QIAN Hui1..舟山地区蝙蝠轮状病毒分子鉴定和分析∗[J].寄生虫与医学昆虫学报,2019,26(1):22-29,8.

基金项目

国家重大传染病专项 (2013ZX1004103-004) (2013ZX1004103-004)

病原微生物生物安全国家重点实验室开放基金 (SKLP2016) (SKLP2016)

江苏省社会发展项目 (BE2017620) (BE2017620)

江苏省333工程资助项目 (BRA2018410) (BRA2018410)

寄生虫与医学昆虫学报

OACSTPCD

1005-0507

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