临床神经外科杂志Issue(2)：123-128,6.DOI:10.3969/j.issn.1672-7770.2019.02.007
多 b 值弥散加权成像术前预测垂体瘤质地的研究
Consistency predicting of pituitary adenomas before operation by multiple b value diffusion- weighted imaging and apparent diffusion coefficient
摘要
Abstract
Objective To explore the application value of Multiple b-Value DWI and ADC in predicting the consistency of pituitary adenomas before operation.Methods 57 patients with pituitary adenoma confirmed pathologically were included in the research .All patients underwent examination , which included 3.0 T MRI multiple b-value (b＝0,1 000,2 000 s／mm2 ) DWI scan and endocrine hormone.Volumes of interest (VOIs) were drawn in the pituitary adenomas on ADC maps generated with two b-values ( b ＝1 000, 2 000 s／mm2 ).Consistency of pituitary adenomas was evaluated at surgery and classified as soft group or hard group.The relationship between the consistency of tumor with mean ADC values , patients’age, gender, hormone classification and collagen contents in tumors were analyzed under two b values.Results There was no statistically significant difference in b1000 ( P＜0.05) but lots of significant difference in b2000 ( P＞0.05) between the tumor consistency and mean ADC values.No other obvious correlations were found between tumor consistency with the patients’age, gender or hormone classification in neither b 1000 nor b2000, but tumor collagen content of soft group were significantly lower than the hard group (both P＜0.05).Conclusions Tumor consistency of pituitary adenomas has close relationship with mean ADC values and collagen contents in tumors but has no relationship with the patient’s gender, age or hormone classification.DW MR images with ADC values can be used to predict the consistency of Pituitary adenomas , which provide important imaging basis for the choice of surgical approach.关键词
MRI/弥散加权成像/表观扩散系数/垂体腺瘤/肿瘤质地/手术入路Key words
MRI/ diffusion-weighted imaging/ apparent diffusion coefficient / pituitary adenomas/ tumor consistency/ surgical approach分类
医药卫生引用本文复制引用
MIAO Zong,WEI Dong,CHEN Gong..多 b 值弥散加权成像术前预测垂体瘤质地的研究[J].临床神经外科杂志,2019,(2):123-128,6.基金项目
国家自然科学基金面上项目[81471269( BA14 )] （ BA14 ）
江苏省科技厅自然科学基金[BK20160047( DA16) ] （ DA16）
