临床神经外科杂志2019，Vol.16Issue(3)：194-198,5.DOI:10.3969/j.issn.1672-7770.2019.03.003
姿态检测装置对帕金森病患者上肢轮替动作的定量评估
Quantitative assessment of upper limb rotation motion in patients with Parkinson’s disease by posture detection device
摘要
Abstract
Objective To explore the feasibility of the posture detection device for quantitative assessment of the rotation motion in Parkinson’s disease(PD) motor function test.Methods Angle signals were collected from 9 patients with PD through a body-worn detection device as the patients carried out the rotation of the upper limb motor function in the Unified Parkinson Rating Scale.After the signal was preprocessed , features including mean , variance, root mean square, amplitude slope, and period slope were extracted from the time domain based on extreme values.Principal Component Analysis was used to reduce the dimensionality of the feature set .In addition, Support Vector Machine( SVM) model was built, and the model score was compared with clinical score. Results Leave-one-out cross validation showed that the SVM model established in this study could accurately evaluate the rotation motion.The probability of model score and clinical score error less than 1 was 0.944.The mean and standard deviation were 0.092 ±0.601 respectively.T-test showed that P＝0.759, which indicates no statistical difference between the two scores.Conclusion The posture detection device can accurately and objectively score the rotation action , which is worthy of clinical promotion.关键词
帕金森病/轮替动作/定量评估/姿态检测装置Key words
Parkinson’s disease/rotation action/digital scoring/attitude detection device分类
医药卫生引用本文复制引用
YANG Fan,WU Xi,SHEN Lin-yong..姿态检测装置对帕金森病患者上肢轮替动作的定量评估[J].临床神经外科杂志,2019,16(3):194-198,5.基金项目
国家自然科学基金(51275282) （51275282）
国家重点研发计划项目(2016YFC0105900) （2016YFC0105900）
