肿瘤预防与治疗2019，Vol.32Issue(1)：25-29,5.DOI:10. 3969／j. issn. 1674-0904. 2019. 01. 004
食管癌术后放疗骨照射剂量与骨髓抑制相关性
Relation Between Bone Irradiation and Bone Marrow Suppression During Postoperative Radiotherapy for Esophageal Carcinoma
Li Cong 1Zhang Xin 1Wu Furong 1Weng Kegui1
作者信息
- 1. Chongqing University Cancer Hospital, Chongqing Cancer Institute, Chongqing Cancer Hospital, Chongqing 400030, China
- 折叠
摘要
Abstract
Objective: To investigate the relation between dose exposure of sternum, vertebra, other bone structures and bone marrow suppression in esophageal cancer patientsundergoing postoperative radiotherapy. Methods: Thirty-eight patients with esophageal cancer who underwent postoperative radiotherapy in our hospital were divided into two groups ( group A:grade <2 hematologic toxicity vs group B: grade≥2 hematologic toxicity) according to hematologic results. Sternum, verte-brae and other bone structures were contoured on planning computed tomography scans. Then the irradiation dose of each bone structures were compared between the two groups. Results: The Dmean,V5 ,V10 ,V20 of total bones, V5 ,V10 of sternum, V5 ,V10 ,V20 of vertebra of group A were higher than those of group B. The differences were statistically significant. Conclu-sion: The irradiation of sternum and vertebra makes more contribution to bone marrow suppression. Difference in the degree of bone marrow suppression in radiotherapywas attributed to lower dose exposure of bone structurerather than higher dose vol-ume.关键词
食管癌/放射治疗/骨照射/骨髓抑制Key words
Esophageal cancer/Radiotherapy/Bone irradiation/Bone marrow suppression分类
医药卫生引用本文复制引用
Li Cong,Zhang Xin,Wu Furong,Weng Kegui..食管癌术后放疗骨照射剂量与骨髓抑制相关性[J].肿瘤预防与治疗,2019,32(1):25-29,5.
