肿瘤预防与治疗2019，Vol.32Issue(3)：238-242,5.DOI:10. 3969／j. issn. 1674-0904. 2019. 03. 007
利用肺部模体研究肺癌在螺旋断层放射治疗计划中靶区间空间关系对肺组织的剂量学影响*
Dosimetric Impact of Spatial Relationship of Radiation Targets in Tomo-therapy on Lung Cancer by Using a Lung Phantom
摘要
Abstract
Objective: To study the impact of several spatial relationships of two targets on absorbed dose received by lung Phantom in the tomotherapy (TOMO) treatment planning system. Methods: On a lung phantom, two targets were contoured in various targets sizes or spatial relationships. Then for each individual way a treatment plan was respectively optimized with rele-vant prescription dose in each TOMO treatment plan. At last, the V5 , V20 and Vmean of lung in each plan were collected and then analyzed by MATLAB. Results: A positive correlation was found between target size and V5 , V20 , Vmean. When the target size was constant, V5 , V20 and Vmean increased with the growth of the distance between two targets till the distance reached a certain threshold beyond which the V5 , V20 and Vmean would not increase anymore. Conclusion: The dose for lung is related to not only the size of lung and that of the tumor but also the relative position of between tumors.关键词
肺部体模/螺旋断层放射治疗/剂量学/肺癌Key words
Lung phantom/Tomotherapy/Eosimetry/Lung cancer分类
医药卫生引用本文复制引用
Wan Bin,Kang Shengwei,Wu Fan,Tang Bin,Wang Pei..利用肺部模体研究肺癌在螺旋断层放射治疗计划中靶区间空间关系对肺组织的剂量学影响*[J].肿瘤预防与治疗,2019,32(3):238-242,5.基金项目
国家重点研发计划项目(编号:2017YFC 0113100) （编号:2017YFC 0113100）
四川省科技重点研发项目(编号:2018GZ0197) This study was supported by the National Key Research and Development Project ( NO. 2017YFC0113100) and the Key Research and Development Project of Science and Technology in Sichuan Province (NO. 2018GZ0197) （编号:2018GZ0197）
