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环状RNA在肝细胞肝癌中的研究进展

Li Yi Wang Feng Ju Shaoqing

肿瘤预防与治疗2019,Vol.32Issue(4):361-365,5.
肿瘤预防与治疗2019,Vol.32Issue(4):361-365,5.DOI:10. 3969/j. issn. 1674-0904. 2019. 04. 013

环状RNA在肝细胞肝癌中的研究进展

Research Progress of Circular RNA in Hepatocellular Carcinoma

Li Yi 1Wang Feng 2Ju Shaoqing1

作者信息

  • 1. Department of Ladoratory Medicine, Affiliated Hospital of Nantong University, Nantong 226001, jiangsu, China
  • 2. School of Pudlic Health, Nantong University, Nantong 226001, jiangsu, China
  • 折叠

摘要

Abstract

Objective: Circular RNA (circRNA) is a special type of endogenous non-coding RNA (ncRNA) with a con-servative structure and conserved sequences. It plays a crucial role in malignancies by affecting the proliferation, apoptosis and invasive capacity of tumor cells. Therefore, circRNA is expected to become a novel biomarker for individualized clinical therapies for tumors. This article reviews the latest study progress of circRNA in hepatocellular carcinoma (HCC), aiming to provide new ideas of the pathogenesis and diagnosis of HCC for clinicians.

关键词

环状RNA/肝细胞肝癌/生物标志物/诊断

Key words

Circular RNA/Hepatocellular carcinoma/Biomarkers/Diagnosis

分类

医药卫生

引用本文复制引用

Li Yi,Wang Feng,Ju Shaoqing..环状RNA在肝细胞肝癌中的研究进展[J].肿瘤预防与治疗,2019,32(4):361-365,5.

基金项目

国家自然科学基金 (编号: 81672099, 81871720, 81873978) (编号: 81672099, 81871720, 81873978)

江苏省六大人才高峰项目(编号:2018WSW068) (编号:2018WSW068)

中国博士后基金项目(编号:2018m642298) This study was supported by the National Natural Science Foundation of China ( NO. 81672099, NO. 81871720, NO. 81873978) , Six Talent Peaks’ Project of Jiangsu Province (NO. 2018WSW068) and the Postdoctoral Science Foundation of China ( NO. 2018m642298). (编号:2018m642298)

肿瘤预防与治疗

OACSTPCD

1674-0904

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