肿瘤预防与治疗2019，Vol.32Issue(5)：429-433,5.DOI:10. 3969/j. issn. 1674-0904. 2019. 05. 008
外周血红细胞宽度检测在食管癌患者临床诊断中的应用价值*
VaIue of PeriPheraI Red BIood CeII Distribution Width in CIinicaI Diagnosis of EsoPhageaI Cancer
摘要
Abstract
To eva1uate the va1ue of PeriPhera1 red b1ood ce11 distribution width (RDW) in c1inica1 diagnosis of esoPha-gea1 cancer. Methods: C1inica1 and b1ood routine examination data of 250 Patients with esoPhagea1 cancer undergoing radica1 resection during January 2017 to December 2017 in Sichuan Cancer HosPita1 were retrosPective1y ana1yzed, and another 250 hea1thy vo1unteers were co11ected at the same time as contro1 grouP for comParative ana1ysis. We drew the ROC curve and found the best truncation va1ue of RDW in the diagnosis of esoPhagea1 cancer. The esoPhagea1 cancer Patients were divided into two grouPs, high and 1ow RDW grouP, according to RDW cut-off va1ue based on ROC curve. ResuIts: The mean 1eve1s of erythrocyte, hemog1obin and 1ymPhocyte in esoPha-gea1 cancer Patients was significant1y 1ower than those in contro1 grouP (P<0. 05), whi1e the 1eve1 of neutroPhi1s in esoPhagea1 cancer Patients was higher than that in contro1 subjects (P<0. 05). The median 1eve1 of RDW in Patients with esoPhagea1 cancer was signifi- cant1y higher than that in contro1 grouP ([12. 8 (12. 6-13. 0) Vs 12. 4 (12. 2-12. 6), Z= -15. 330, P<0. 001]. More than 60 years o1d, Ⅲ ~ Ⅳ stage in tumor staging and distant metastasis were Positive1y corre1ated with the increase of RDW (P<0. 05). In sPecific, the risk of increased RDW in esoPhagea1 cancer Pa- tients over 60 was 2. 989 times greater than in those not more than 60; that in Ⅲ~Ⅳ stage esoPhagea1 cancer Patients was 3. 861 times greater than inⅠ~Ⅱstage esoPhagea1 cancer Patients; and that was 6. 013 times greater in esoPhagea1 cancer Patients with dis-tant metastasis comPared with those without distant metastasis. ConcIusion: As a fast, simP1e, economica1 and easi1y obtained bio1ogi-ca1 index, RDW va1ue can be used as an index for the c1inica1 diagnosis and Prediction of the severity of esoPhagea1 cancer.关键词
食管癌/红细胞分布宽度/临床诊断/应用价值Key words
EsoPhagea1 cancer/Reb1ooce11 distribution width/C1inica1 diagnosis/APP1ication va1ue引用本文复制引用
Li Shi,Song Xiaoyu,Zhang Li,Luo Huaichao,He Qiao..外周血红细胞宽度检测在食管癌患者临床诊断中的应用价值*[J].肿瘤预防与治疗,2019,32(5):429-433,5.基金项目
吴阶平医学基金(编号:320. 6750. 14273) This study was suPPorted by Wu JiePing Medica1 Foundation ( NO. 320. 6750. 14273). （编号:320. 6750. 14273）
