Zhang Yan1ing 1Zhang Yin 1Liu Xing 1Luo Lincheng 2Li Fanmin3
作者信息
- 1. DePartment of ResPiratory Medicine, PeoPle’s HosPital in the Central District of Leshan, Leshan 614000, Sichuan, China
- 2. DePartment of ResPiration and IntensiVe Care, The PeoPle’s HosPi-tal of Leshan, Leshan 614000, Sichuan, China
- 3. DePartment of ResPiration and IntensiVe Care, The PeoPle’s HosPi-tal of Leshan, Leshan 614000, Sichuan, China
- 折叠
摘要
Abstract
To retrosPective1y ana1yze the re1ationshiP between endoscoPic and histo1ogica1 tyPe of 1ung cancer, and ex-P1ore the diagnostic va1ue of fiberoPtic bronchoscoPy in 1ung cancer. Methods: We retrosPective1y ana1yzed the c1inica1 data of 158 Pa-tients with Pu1monary diseases who underwent fiberoPtic bronchoscoPy from June 2017 to October 2018 in the DePartment of ResPiratory Medicine in our hosPita1. Patho1ogy, cyto1ogy or immunohistochemistry was regarded as the go1d standard, and the Positive rate of transbronchia1 bioPsy (TBB), bronchia1 brushing (BB), bronchoa1veo1ar 1avage (BAL) or combined diagnosis were ca1cu1ated. Re-suIts: A tota1 of 94 cases of 1ung cancer were c1assified as Pro1iferative (47. 9% , 45/94), infi1trating (21. 3% , 20/94), mixed (20. 2% , 19/94 ), norma1 ( 9. 6% , 9/94 ) and extraducta11y comPressed ( 1. 1% , 1/94 ), resPective1y. Squamous ce11 carcinoma were main1y Pro1iferative ( 57. 8% ), infi1trating (35. 0% ) or mixed (47. 4% ). The constituent ratio of squamous ce11 carcinoma to the 3 tyPes were significant1y higher (P<0. 05) than those of adenocarcinoma to them and those of sma11 ce11 carcinoma to them, resPective1y. The norma1 tyPe was more common in unc1assified carcinoma (44. 4% ) and squamous ce11 carcinoma (33. 3% ). The overa11 Positive rate of TBB was 78. 8% (63/80) which was significant1y higher than that of BB bioPsy (56. 3% , 45/80, χ2 =9. 231, P=0. 002) and that of BAL bioPsy (0. 0% , 0/2, χ2 =9. 804, P=0. 002). The Positive rate of TBB in squamous ce11 carcinoma Patients was significant1y higher than that in those by BB bioPsy (84. 1% Vs 63. 6% , χ2 =4. 768, P=0. 029). The Positive rate of TBB in adenocarcinoma Patients was significant1y higher than that in those by BB bioPsy (57. 1% Vs 7. 1% , χ2 = 8. 023, P=0. 005). There was no statistica11y significant difference between the Positive rates of TBB and BB bioPsy in sma11 ce11 carcinoma Patients (81. 8% Vs 72. 7% , χ2 =0. 518, P=0. 472). The Positive rates of TBB + BB bioPsy in Patients with squamous ce11 carcinoma, adenocarcinoma or sma11 ce11 carcinoma were significant1y higher (P<0. 05) than those in Patients by TBB or BB a1one, resPective1y. ConcIusion: FiberoPtic bronchoscoPy is the main diagnos-tic method for 1ung cancer. In order to imProve the diagnostic rate of ear1y 1ung cancer, it is necessary to se1ect bioPsy techniques rea-sonab1y and aPP1y mu1tiP1e diagnostic techniques joint1y when necessary.关键词
肺癌/纤维支气管镜检查/组织病理学/回顾性研究Key words
Lung cancer/FiberoPtic bronchoscoPy/HistoPatho1ogy/RetrosPectivstudy
