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卵圆孔未闭与隐源性卒中的研究进展

CHEN Zhu-Lin HUANG Guang

中国卒中杂志2019,Vol.14Issue(5):456-462,7.
中国卒中杂志2019,Vol.14Issue(5):456-462,7.DOI:10.3969/j.issn.1673-5765.2019.05.010

卵圆孔未闭与隐源性卒中的研究进展

Progress in Patent Foramen Ovale and Cryptogenic Stroke

CHEN Zhu-Lin 1HUANG Guang1

作者信息

  • 1. Department of Neurology, Fuxing Hospital, Capital Medical University, Beijing 100038, China
  • 折叠

摘要

Abstract

Cryptogenic stroke accounts for about 40% of all ischemic stroke. Its etiology, diagnosis and treatment have been the focus of clinical research. It has been found that patent foramen ovale (PFO) is closely related to cryptogenic stroke, and it is an important risk factor for cryptogenic stroke. PFO can be detected by transesophageal echocardiography, transthoracic echocardiography, transcranial Doppler foaming test and cardiac MRI. Paradoxical embolism is the main pathogenesis of occult stroke caused by PFO. The imaging features in most PFO-related cryptogenic stroke patients are multiple scattered small lesions in multiple vascular territories. Antiplatelet may be more suitable than anticoagulants therapy for most cryptogenic stroke patients with PFO. In addition, recent randomized controlled trials indicated that PFO closure was superior to drug therapy in preventing stroke recurrence in cryptogenic stroke patients with PFO.

关键词

卵圆孔未闭/隐源性卒中/反常栓塞/治疗

Key words

Patent foramen ovale/Cryptogenic stroke/Paradoxical embolism/Treatment

引用本文复制引用

CHEN Zhu-Lin,HUANG Guang..卵圆孔未闭与隐源性卒中的研究进展[J].中国卒中杂志,2019,14(5):456-462,7.

中国卒中杂志

OACSTPCD

1673-5765

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