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西达本胺抗肿瘤作用机制的研究进展

LI Jieyao XU Wanting ZHUO Ran LI Mingbo ZHANG Yu ZHANG Tong LUO Yinghua JIN Chenghao

肿瘤药学2019，Vol.9Issue(1)：6-9,25,5.

肿瘤药学2019，Vol.9Issue(1)：6-9,25,5.DOI:10.3969/j.issn.2095-1264.2019.01.02

西达本胺抗肿瘤作用机制的研究进展

The Research Progress of Chidamide Antitumor Mechanism★

LI Jieyao ¹XU Wanting ¹ZHUO Ran ¹LI Mingbo ¹ZHANG Yu ¹ZHANG Tong ¹LUO Yinghua ¹JIN Chenghao¹

作者信息

1. College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang, 163319, China
折叠

摘要

Abstract

Chidamide is an oral inhibitor of subtype selective histone deacetylase (HDAC), which can not only resist epilepsy, but also has good anti-tumor activity. It can exert anti-tumor activity by inducing cell apoptosis and differentiation, blocking cell cycle, inhibiting new angiogenesis and regulating the levels of ROS. This article will illustrate the antitumor pharmacological activity and mechanism of Chidamide.

关键词

西达本胺/肿瘤/细胞凋亡

Key words

Chidamide/ Tumor/ Apoptosis

分类

医药卫生

引用本文复制引用

LI Jieyao,XU Wanting,ZHUO Ran,LI Mingbo,ZHANG Yu,ZHANG Tong,LUO Yinghua,JIN Chenghao..西达本胺抗肿瘤作用机制的研究进展[J].肿瘤药学,2019,9(1):6-9,25,5.

基金项目

基金项目:黑龙江省科学基金项目(LC2015036) （LC2015036）

黑龙江省大学生创新创业训练计划项目(201710223001). （201710223001）

肿瘤药学

OACSTPCD

ISSN：2095-1264

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