肿瘤药学2019，Vol.9Issue(1)：130-132,148,4.DOI:10.3969/j.issn.2095-1264.2019.01.28
消癌平注射液联合表柔比星新辅助化疗治疗三阴性乳腺癌的临床疗效
Clinical Efficacy of Xiao’aiping Injection Combined with Epirubicin Neo-adjuvant Chemotherapy for Triple Negative Breast Cancer
YANG Xiaozhong 1WANG Ying 1DANG Nan 1DONG Jiaqing 1MA Wenxia1
作者信息
- 1. The Second Affiliated Hospital of Xi’an Medical University, Xi’an, Shaanxi, 710038, China
- 折叠
摘要
Abstract
Objective To explore the clinical efficacy of Xiao'aiping injection combined with neo-adjuvant chemotherapy with epiru-bicin in the treatment of triple negative breast cancer. Methods Eighty patients diagnosed with triple-negative breast cancer in our hospital were selected and divided into two groups by random number table. The patients in the control group were treated with epirubicin alone. And those in observation group were treated with Xiao'aiping injection and epirubicin. The clinical efficacy, levels of IL-6, IL-8, TNF-α, quality of life, and adverse reactions before and after treatment were compared between the two groups. Results The clinical efficacy of the observation group was significantly better than that of the control group (P<0.05). There was no significant difference in the levels of IL-6, IL-8 and TNF-α before treatment between the two groups (P>0.05). After treatment, the levels of IL -6 and IL-8 were significantly lower in observation group than in control group (P<0.05), while the TNF-α level was higher in observation group than in control group (P<0.05). Before treatment, there were no significant differences in the scores of body, role, cognition, emotion and social function between the two groups (P>0.05). However, after treatment, the scores of the above mentioned were significantly higher in observation group than in con-trol group (P<0.05). The adverse reactions in the observation group were significantly less than in the control group (P<0.05). Conclusion Xiao'aiping injection combined with epirubicin neoadjuvant chemotherapy is effective for triple negative breast cancer pateints. It is worthy of extensive clinical application.关键词
消癌平注射液/表柔比星/三阴性乳腺癌/新辅助化疗/临床疗效Key words
Xiao'aiping injection/ Epirubicin/ Triple negative breast cancer/ Neoadjuvant chemotherapy/ Clinical efficacy分类
医药卫生引用本文复制引用
YANG Xiaozhong,WANG Ying,DANG Nan,DONG Jiaqing,MA Wenxia..消癌平注射液联合表柔比星新辅助化疗治疗三阴性乳腺癌的临床疗效[J].肿瘤药学,2019,9(1):130-132,148,4.
