肿瘤药学2019,Vol.9Issue(2):287-290,4.DOI:10.3969/j.issn.2095-1264.2019.02.23
吉西他滨联合阿霉素对肝癌患者生活质量的影响及疗效分析
Effect of Gemcitabine Combined with Adriamycin on the Quality of Life of Hepatocellular Carcinoma Patients and its Curative Effect
WANG Xudong 1WANG Fa 1LV Da 2FU Huimin 3CUI Shejuan4
作者信息
- 1. Minimally Invasive Interventional Department, Qingdao Municipal Hospital, Qingdao, Shandong, 266000, China
- 2. Oncology Department,Qingdao Municipal Hospital, Qingdao, Shandong, 266000, China
- 3. Imaging Department, Qingdao Municipal Hospital, Qingdao, Shandong, 266000, China
- 4. Department of Ultrasound, Qingdao Haici Medical Group, Qingdao, Shandong, 266000, China
- 折叠
摘要
Abstract
Objective To investigate the effects of gemcitabine combined with adriamycin on the quality of life of liver cancer patients and its curative effects. Methods A total of 288 cases of liver cancer treated in our hospital were randomly divided into two groups. The control group was treated with conventional therapy plus gemcitabine, and the observation group was treated with conventional therapy plus gemcitabine combined with adriamycin. The changes in the index of liver fibrosis, the efficiency of drug treatment, the changes of liver func-tion and the life quality scores were compared between the two groups. Results After treatment, the effective rate of the observation group was significantly higher than that of the control group (P<0.05). Before treatment, there were no differences between the two groups in the results of liver fibrosis indexes and liver function indexes (P>0.05). But after treatment, the results of liver fibrosis indexes were significantly lower in observation group than in control group (P<0.05). The levels of liver function indexes of the observation group were also better than those of the control group (P<0.05). Besides, the quality of life scores of the observation group was significantly higher than that of the con-trol group (P<0.05). Conclusion Gemcitabine combined with adriamycin had good curative effect on liver cancer patients. It could improve the life quality of the patients. So it is worthy of further clinical application and promotion.关键词
肝癌/吉西他滨/阿霉素/疗效/生活质量Key words
Liver cancer/Gemcitabine/Adriamycin/Effect/Quality of life分类
医药卫生引用本文复制引用
WANG Xudong,WANG Fa,LV Da,FU Huimin,CUI Shejuan..吉西他滨联合阿霉素对肝癌患者生活质量的影响及疗效分析[J].肿瘤药学,2019,9(2):287-290,4.