肿瘤药学2019，Vol.9Issue(2)：300-303,4.DOI:10.3969/j.issn.2095-1264.2019.02.26
康莱特对晚期乳腺癌患者肿瘤标志物及生存质量的影响
Effects of Kanglaite on Tumor Markers and Quality of Life of Patients with Advanced Breast Cancer
摘要
Abstract
Objective To investigate the effect of Kanglaite on serum tumor markers and quality of life in patients with advanced breast can-cer. Methods Eighty-eight patients with advanced breast cancer enrolled in our hospital were randomly divided into control group and observa-tion group. The control group got symptomatic treatment and nutritional support, while the observation group was added with Kanglaite injection on the basis of treatment of control group. The efficiency of treatment, changes of hemoglobin, leukocyte, platelet and tumor markers before and after treatment, and the Karnofsky scores were compared between the two groups. Results The total efficiency of the observation group was sig-nificantly higher than that of the control group (P<0.05). The levels of hemoglobin, leukocyte, CA15-3, CA125 and CEA, and the platelet count of patients after treatment all were lower than those before treatment (P<0.05) in both groups. In addition, they were all lower in the observation group than in the control group after treatment (P<0.05). The observation group also achieved a higher improvement rate of Karnofsky score than the control group (P<0.05). Conclusion Kanglaite had good effects in the treatment of advanced breast cancer. It could strengthen the treatment efficiency, reduce the levels of tumor markers, and improve the life quality of patients, so it is worthy of clinical promotion.关键词
康莱特/晚期乳腺癌/肿瘤标志物/生存质量Key words
Kanglaite/Advanced breast cancer/Tumor markers/Quality of life分类
医药卫生引用本文复制引用
CHEN Shanshan,LIU Fangfang,LIU Zishuang,ZHANG Xinfeng,WEI Li..康莱特对晚期乳腺癌患者肿瘤标志物及生存质量的影响[J].肿瘤药学,2019,9(2):300-303,4.基金项目
国家自然科学基金资助项目(81171435). （81171435）
