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脑复康方改善神经胶质瘤术后的疗效及安全性观察

DENG Tingting WANG Yunqi XU Kang

肿瘤药学2019,Vol.9Issue(2):308-311,4.
肿瘤药学2019,Vol.9Issue(2):308-311,4.DOI:10.3969/j.issn.2095-1264.2019.02.28

脑复康方改善神经胶质瘤术后的疗效及安全性观察

Effect of Naofukang Decoction on Improving Postoperative Glioma

DENG Tingting 1WANG Yunqi 2XU Kang3

作者信息

  • 1. Hunan University of Chinese Medicine, Changsha, Hunan, 410006, China
  • 2. Department of TCM / Integrated Medicine, Hunan Cancer Hospital, Changsha, Hunan, 410013, China
  • 3. Shaanxi University of Traditional Chinese Medicine, Xi’an, Shaanxi, 712000, China
  • 折叠

摘要

Abstract

Objective To observe the clinical efficacy and safety of Naofukang decoction in postoperative patients with glioma. Methods Fifty-two patients with high-grade glioma were selected and randomly divided into two groups. In the control group, 26 cases were treated with simple radiochemotherapy. In the treatment group, 26 cases were treated with radiotherapy plus Naofukang decoction. Compare the total effectiveness, Karnofsky (KPS) functional status and toxicity between the two groups. Results The total effective rate was slightly higher in treatment group than in control group, but there was no statistical difference (P>0.05). Compared with before treatment, the KPS scores were increased in both groups after treatment, and they were even increased much greater in treatment group than in control group (P<0.05). The incidence of the adverse reactions was significantly lower in treatment group than in control group (P<0.05). Conclusion Naofukang decoc-tion could alleviate the side effects of postoperative radiochemotherapy in patients with high-grade glioma, so that could improve the quality of life of patients.

关键词

神经胶质瘤/术后/脑复康方/KPS评估/毒副反应

Key words

Glioma/Postoperative/Rehabilitation brain/KPS assessment/Toxic side effects

分类

医药卫生

引用本文复制引用

DENG Tingting,WANG Yunqi,XU Kang..脑复康方改善神经胶质瘤术后的疗效及安全性观察[J].肿瘤药学,2019,9(2):308-311,4.

基金项目

湖南省中医药管理局资助项目(201535). (201535)

肿瘤药学

OACSTPCD

2095-1264

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