肿瘤预防与治疗2019，Vol.32Issue(8)：707-710,4.DOI:10.3969/j.issn.1674-0904.2019.08.009
呼吸门控技术以及非均整模式应用于早期非小细胞肺癌小病灶立体定向放疗的优势✲
Advantages of Stereotactic Body Radiation Therapy Using Flattening Filter Free Techniques and Active Breathing Control for Early-Stage Non-Small Cell Lung Cancer with Small Lesions
摘要
Abstract
Objective: To investigate advantages of active breathing control and flattening filter free (FFF) techniques o-ver traditional stereotactic body radiation therapy (SBRT) in total treatment time (TTT), setup error and radiation dosimetry for early-stage non-small cell lung cancer ( NSCLC) patients. Methods: A total of 26 NSCLC patients with small lesions were selected as subjects in Radiation Technology Center of Harbin Medical University Cancer Hospital from 2017 to 2018. Subjects were assigned to group A (SBRT with flattened model, n=10), group B (SBRT with FFF techniques, n=8) and group C (SBRT with ABC and FFF techniques, n=8). We analyzed setup errors in X, Y and Z direction. Data were re- trieved from registered images. We compared differences among 3 groups in TTT, setup errors, target delineation, and V5 , V20 and dosimetry of the affected lobe. Results: TTT in group C was significantly shorter than that in group A ( P < 0. 05), and no obvious difference was found between group B and group C (P>0. 05). Machine unit／TTT in group C was significantly more than that in group A. The setup error in group C was the smallest (P<0. 05). V5 and V20 of the affected lobe in group C were lower than that in group A and that in group B (P<0. 05). Conclusion: Active breathing control and FFF techniques have obvious advantages in the treatment of early-stage NSCLC with small lesions such as shorter treatment time, higher patient comfort, smaller error and better protection for the affected lobe.关键词
非均整模式/呼吸门控/非小细胞肺癌/立体定向放射治疗Key words
Flattening filter free model/Active breathing control/Non-small cell lung cancer/Stereotactic body radia-tion therapy分类
医药卫生引用本文复制引用
刘穆平,初磊,邓煜,韩宇,许庆勇,陈林..呼吸门控技术以及非均整模式应用于早期非小细胞肺癌小病灶立体定向放疗的优势✲[J].肿瘤预防与治疗,2019,32(8):707-710,4.基金项目
黑龙江省自然科学基金项目(编号:D201154) This study was supported by Natural Science Foundation of Heilongjiang Province ( NO. D201154). （编号:D201154）
