肿瘤预防与治疗2019，Vol.32Issue(8)：730-735,6.DOI:10.3969/j.issn.1674-0904.2019.08.013
低温等离子刀与喉部分切除术治疗早期声门型喉癌的疗效及安全性分析✲
Efficacy and Safety of Low Temperature Plasma Knife and Partial Laryn-gectomy in the Treatment of Early Glottic Cancer
摘要
Abstract
Objective: To study the efficacy and safety of low temperature plasma knife and partial laryngectomy in the treatment of early glottic cancer. Methods: A total of 62 patients with early glottic cancer who underwent surgery in our hospital from February 2013 to February 2016 were selected for the study and were assigned to the observation group and the control group by using a random number table, with 31 ca- ses in each group. They were treated by low temperature plasma radiofrequency ablation technique and partial laryngectomy, respectively. Surgical outcomes, postoperative rehabilitation and incidence of complications were compared between groups. Results: Operation time, intraoperative blood loss and length of stay in the observation group were lower than those in the control group (P<0. 05). Recovery of voice in the observation group was significantly better than that in the control group 6 months after operation (P<0. 05). 93. 55% of patients’ voice in the observation group and 74. 19% of patients’ voice in the control group was in excellent or good condition (P<0. 05). Videofluorographic swallowing study (VFSS) score in the observation group was significantly higher than that in the control group (P<0. 05), but there was no significant difference in recovery of swallowing function between the two groups (P>0. 05). During 3 years of follow up, there were no significant differences in local recurrence, lymph node metastasis, distant metastasis and death between the two group (P>0. 05). In-cidence of postoperative granulation tissue hyperplasia in the observation group was significantly lower than that in the control group (P<0. 05), and there were no significant differences in the incidence of wound infection, pharyngeal fistula, stenosis of the larynx and pharynx and aspiration pneumonia between the two groups (P>0. 05). Conclusion: Low temperature plas-ma radiofrequency ablation technique has a similar efficacy to partial laryngectomy in the treatment of early glottic cancer. The former is minimally invasive with speedy recovery, fewer complications, and good postoperative voice and swallowing function, and its efficacy and safety is widely recognized.关键词
声门型喉癌/早期/喉部分切除术/低温等离子刀/疗效/安全性Key words
Glottic cancer/Early stage/Partial laryngectomy/Low temperature plasma knife/Efficacy/Safety分类
医药卫生引用本文复制引用
郑跃彬,鄢斌成,蔡永聪,段礼府,徐小鸿,杨羿容..低温等离子刀与喉部分切除术治疗早期声门型喉癌的疗效及安全性分析✲[J].肿瘤预防与治疗,2019,32(8):730-735,6.基金项目
四川省科技厅重点研发项目(编号:2019 YFS0337) This study was supported by grants from Science & Technology Department of Sichuan Province (2019YFS0337). （编号:2019 YFS0337）
