烟草科技2019，Vol.52Issue(8)：44-51,8.
GC-MS/MS法结合多元统计过程控制应用于烟用香精的质量监控
GC-MS/MS combining with multivariate statistical process control for quality monitoring of tobacco flavor
摘要
Abstract
To monitor the quality of tobacco flavor via aroma components, a GC-MS/MS (gas chromatography-tandem mass spectrometry) method was established for simultaneously determining all aroma components in tobacco flavors. Furthermore, a quality monitoring model for tobacco flavors was developed on the basis of MSPC (multivariate statistical process control). The flavor samples were separated on a DB-WAX column after extracted with acetone at the sample/solvent ratio of 1∶20 and ultrasonic extraction time of 5 min. The extracts were analyzed by GC-MS/MS under the multi-reaction monitoring (MRM) mode, and internal standard correction method was applied to semi-quantify aroma components. Statistic Hotelling T 2 was calculated by a PCA-based MSPC method combining with the sensory evaluation of cigarettes, and a control chart was drawn by taking 3σ as the upper control limit to assess the quality of tobacco flavors. The results showed that the LODs of the most aroma components were less than 1.0 ng/mL, the recoveries ranged from 80% to 120% with the intra- and inter-day relative standard deviations (RSDs) less than 3% and 5% respectively. This method features a high sensitivity and good accuracy. The quality monitoring model based on the analysis of all aroma components objectively reflects the intrinsic quality fluctuation of tobacco flavors and is suitable for the rapid and accurate evaluation of tobacco flavor quality.关键词
GC-MS/MS/多元统计过程控制/烟用香精/质量监控Key words
GC-MS/MS/Multivariate statistical process control/Tobacco flavor/Quality monitoring分类
通用工业技术引用本文复制引用
蒋成勇,杜国荣,王丽达,张杰,严莉红,白若石,郑晓曼,芦楠,周骏..GC-MS/MS法结合多元统计过程控制应用于烟用香精的质量监控[J].烟草科技,2019,52(8):44-51,8.基金项目
上海烟草集团有限责任公司科技项目"烟用香精的质量控制方法研究及其在卷烟产品质量监控中的应用"(K2017-2-014P). （K2017-2-014P）
