临床神经外科杂志2019，Vol.16Issue(5)：397-401,5.DOI:10.3969／j.issn.1672-7770.2019.05.006
脑血运重建治疗缺血性烟雾病手术时机的选择
Optimum operation time of revascularization for ischemic moyamoya disease
摘要
Abstract
Objective To discuss the optimum operation time for ischemic moyamoya disease. Methods The clinical data of 41 patients with ischemic moyamoya disease underwent revascularization at the Department of Neurosurgery , Renmin Hospital of Wuhan University from June 2016 to May 2018 were analyzed retrospectively.Considering the time interval between acute onset of moyamoya disease and surgery, all patients were divided into early group and later group (＞90 days between MMD onset and surgery ).The post-operation complication ( Cerebral hemorrhage , Cerebral infarction , Cerebral hyperperfusion ), and the effective of operation (the score of NIHSS, the improvement of perfusion ) were compared between groups to estimate optimum operative time of revascularization .Results Compared with the later group , the difference was statistically significant in early group about the improvement of perfusion and neurofunction (P＜0.05), the values were 0.00 and 0.01, respectively. There was no obvious difference about post-operation complication between early group (52.9%) and later(54.2%) group.Conclusions It seems more reasonable to operate for early revasculization for patients with ischemic moyamoya disease.It can improve surgical efficacy and the risk of postoperative hyperperfusion , cerebral infarction and cerebral hemorrhage may not increase .关键词
烟雾病/血运重建/手术时机Key words
moyamoya disease / revascularization/ timing of operation分类
医药卫生引用本文复制引用
欧阳光,黄书岚,徐海涛,余小祥..脑血运重建治疗缺血性烟雾病手术时机的选择[J].临床神经外科杂志,2019,16(5):397-401,5.基金项目
湖北省卫生健康委员会科研项目(WJ2019M196) （WJ2019M196）
