临床神经外科杂志2019，Vol.16Issue(5)：402-405,409,5.DOI:10.3969／j.issn.1672-7770.2019.05.007
颞浅动脉-大脑中动脉分支吻合联合脑-硬脑膜-肌肉血管融合术治疗烟雾病的效果及对脑血循环的影响
Comparison of STA-MCA+EDMS and conservative therapy for moyamoya disease and its effect on cerebral circulation
朱耀祖 1陈锋 1王旭 1刘汉东 1敖祥生 1张海泉1
作者信息
- 1. 441021 襄阳,湖北文理学院附属医院,襄阳市中心医院神经外科
- 折叠
摘要
Abstract
Objective To explore the effect of superficial temporal artery-brain middle artery branch anastomosis combined with brain-dural-muscle fusion(STA-MCA+EDMS) and conservative treatment of moyamoya disease ( MMD) and its effect on Vm and PI.Methods A total of 160 patients with MMD between May 2015 and May 2018 were randomly divided into two groups , 80 in each group.The control group was treated with conservative therapy and the observation group was treated with STA-MCA +EDMS.The clinical efficacy of the two groups was compared.The mean velocity and pulse index values of the two groups were detected and compared , and the prognosis and mortality of the two groups were followed up.Results The Matsushima classification results of the observation group were better than the control group ( P ＜0.05 ).There was no significant difference in Vm and PI levels between the two groups before treatment ( P＞0.05 ).There was a significant improvement in the 3 months after treatment ( all P＜0.001), in which the Vm of the observation group was significantly higher than that of the control group ( P＜0.001).There was no significant difference in mRS score between the two groups before treatment ( P ＞0.05 ).There was a significant improvement in the 3 months after treatment, and the mRS score of the observation group was significantly lower than that of the control group ( P ＜0.001 ).The rebleeding and mortality in the observation group were significantly lower than those in the control group ( all P＜0.001).Conclusion Compared with conservative therapy , STA-MCA +EDMS has a better clinical effect on MMD, and is more conducive to the improvement of the intracranial branch microcirculation, reducing the symptoms of patients and reducing the occurrence of rebleeding and death.关键词
烟雾病/颞浅动脉-大脑中动脉分支吻合联合脑-硬脑膜-肌肉血管融合/保守治疗Key words
moyamoya disease / STA-MCA+EDMS/ conservative treatment分类
医药卫生引用本文复制引用
朱耀祖,陈锋,王旭,刘汉东,敖祥生,张海泉..颞浅动脉-大脑中动脉分支吻合联合脑-硬脑膜-肌肉血管融合术治疗烟雾病的效果及对脑血循环的影响[J].临床神经外科杂志,2019,16(5):402-405,409,5.
