动物营养学报2019，Vol.31Issue(8)：3431-3437,7.DOI:10.3969/j.issn.1006⁃267x.2019.08.001
黄烷醇对动物胰岛素抵抗状态下血糖稳态的调控作用及其机理
Regulation of Flavanols on Blood Glucose Homeostasis in Insulin Resistant Animal and Its Mechanisms
摘要
Abstract
Blood glucose homeostasis plays an important role in various physiological functions of animals. Fla?vanols is a kind of bioflavonoids derived from plants. Studies have proved that flavanols can maintain blood glucose homeostasis in insulin resistant animals. The mechanisms may involve regulating digestion and absorp?tion efficiency of intestinal carbohydrates, increasing the activity of glucagon like peptide?1, promoting insulin secretion in islet beta cells, enhancing the efficiency of liver glycogen synthesis and decreasing inflammatory reaction to protect insulin signal transduction pathway from disruption. This paper briefly reviewed the regula?tion of flavanols on blood glucose homeostasis in insulin resistant animal and its mechanisms, and aimed to pro?vide a basis for its application in animal husbandry and clinical treatment.[ Chinese Journal of Animal Nutri?tion, 2019, 31(8) :3431?3437]关键词
黄烷醇/胰岛素抵抗/血糖稳态/作用机理Key words
flavanols/insulin resistance/blood glucose homeostasis/mechanism分类
农业科技引用本文复制引用
张珍誉,赵华,陈小玲,贾刚..黄烷醇对动物胰岛素抵抗状态下血糖稳态的调控作用及其机理[J].动物营养学报,2019,31(8):3431-3437,7.基金项目
"十三五"国家重点研发项目(2017YFD0502000) （2017YFD0502000）
