动物营养学报2019,Vol.31Issue(8):3496-3504,9.DOI:10.3969/j.issn.1006⁃267x.2019.08.009
氧化应激的产生及其对畜禽肝脏功能的影响与机制
Generation of Oxidative Stress as well as Its Effect and Mechanism on Liver Function of Livestock and Poultry
摘要
Abstract
In the large scale production of modern animal husbandry, many factors induce animals’ oxidative stress, such as breeding environment, diet composition, feeding methods and so on. Oxidative stress has a neg?ative effect on the liver function of livestock and poultry, and endangers the health and production of animals. When oxidative stress occurs in the body, a large amount of oxygen free radicals accumulate in the liver cells, damage the liver macromolecular substances, destroy the structure of the liver cells, affect the function of or?ganelles, induce apoptosis of liver cells, and cause a variety of injuries to the liver. In order to provide a theo?retical basis for alleviating the hazards of oxidative stress, this paper reviews the generation of oxidative stress in the body, the effect of oxidative stress on liver function, as well as the possible molecular mechanisms of the effect.[ Chinese Journal of Animal Nutrition, 2019, 31(8) :3496?3504]关键词
活性氧/氧化应激/畜禽/肝脏损伤Key words
reactive oxygen species/oxidative stress/livestock and poultry/liver injury分类
农业科技引用本文复制引用
苗启翔,谢彦娇,唐湘方,张宏福..氧化应激的产生及其对畜禽肝脏功能的影响与机制[J].动物营养学报,2019,31(8):3496-3504,9.基金项目
国家重点研发专项(2018YFD0500703,2016YFD0500501) (2018YFD0500703,2016YFD0500501)
国家肉鸡产业体系(ASTIP⁃IAS07) (ASTIP⁃IAS07)