中风与神经疾病杂志2019，Vol.36Issue(8)：717-721,5.
25羟基维生素D与脑梗死体积的相关性研究
Correlation between 25 hydroxyvitamin D and cerebral infarction volume
摘要
Abstract
Objective To investigate the relationship between 25-hydroxyvitamin D [25(OH) D] and infarct vol-ume in acute ischemic stroke. Methods One hundred and seventy-four patients with acute ischemic stroke admitted to the neurology department of the second affiliated hospital of baotou medical college from January 2017 to December 2018 were collected,and 186 healthy middle-aged and elderly patients with complete stroke screening out patient data were collected. According to the infarct volume of the cranial NMR,the patients were divided into three groups:small infarct size group (in-farct volume<20 cm3 ),1 cm3 < medium infarct size group <20 cm3 , and large infarct size group ( infarct volume≥20 cm3). Differences in 25(OH) D and peripheral blood biochemical indexes were analyzed between the three groups. In-farct volume grouping was used as the dependent variable,carotid intima media thickness grouping and vascular stenosis grouping were used as the conjunctive factors,and 25(OH)D grouping as the independent variable for multivariate ordered logistic regression analysis. Results The differences of 25(OH) D among the three groups (14. 51 ± 4. 10 ng/L,12. 15 ± 3. 30 ng/L,9. 67 ± 2. 61 ng/L) were statistically significant (P=0. 000). Multiple logistic regression analysis showed that after confounding factors were excluded,compared with the normal group,the possibility of increasing infarct volume by one grade in the 25 (OH) D deficiency group and the deficiency group was 2. 826 (P=0. 020) and 1. 146 (P=0. 764) times of the normal group,respectively. Conclusion 25 (OH) D deficiency is related to the increase of infarct volume.关键词
25-羟基维生素D/ 脑梗死/ 梗死体积Key words
25-hydroxyvitamin D/ Cerebral infarction/ Infarct volume分类
医药卫生引用本文复制引用
冯彩霞,王增帅,乌兰,高丽芝,王惠珍..25羟基维生素D与脑梗死体积的相关性研究[J].中风与神经疾病杂志,2019,36(8):717-721,5.基金项目
包头医学院科学研究基金项目扬帆计划( No. BYJJ-YF 201740) （ No. BYJJ-YF 201740）
