摘要
Abstract
Objective To evaluate the predictive value of asymmetrical cortical vein sign (ACVS) based on SWI for clinical outcome at 3 months in patients with acute ischemic stroke (AIS). Methods Data of AIS patients with infarction in middle cerebral artery (MCA) territory from Department of Neurology, the Third Hospital of Hebei Medical University were collected. All patients underwent DWI, SWI and time of flight (TOF) MRA examination within 7 days after symptom onset, and ACVS, the degree of MCA stenosis and infarct size in all patients were evaluated. Stroke severity on admission was assessed by NIHSS, and the outcome at 3 months was assessed by mRS. Based on the SWI findings, the patients were divided into ACVS group and symmetrical cortical venous group. Univariate analysis and multivariate logistic regression analysis were used to evaluate the value of ACVS in predicting the 3-month prognosis. Results A total of 125 patients were enrolled in this study, with symmetrical cortical venous in 95 (76.0%) patients and ACVS in 30 (24.0%) patients. Compared with symmetrical cortical venous group, MCA severe stenosis or occlusion were more common (76.7% vs 45.3%, P=0.003), DWI-ASPECTS score was lower (7.5 vs 8.0, P=0.018), and NIHSS score on admission was higher (4.5 vs 40, P=0.042) in ACVS group. There was no significant difference in 3-month outcome between the two groups (63.3% vs 44.2%, P=0.093). After adjusting for the confounding factors, logistic regression analysis indicated ACVS was not an independent predictive factor of the 3-month outcome in AIS patients. Conclusions ACVS is related to the degree of MCA stenosis, infarct size and NIHSS score on admission in AIS patients, but it can’t independently predict the prognosis at 3 months after stroke onset.关键词
卒中/磁敏感加权成像/不对称皮层静脉征/氧摄取分数Key words
Stroke/Susceptibility weighted imaging/Asymmetrical cortical vein sign/Oxygen extraction fraction
