动物营养学报2019，Vol.31Issue(9)：4000-4007,8.DOI:10.3969／j.issn.1006⁃267x.2019.09.011
基于代谢组学的乳汁中代谢物研究进展
Advances on Metabolites in Human and Animal Milks Based on Metabolomics
摘要
Abstract
Breast milk is the best food to provide essential nutrients for the growth and development of newborn mammals. The breast milk can provide nutrition for newborn mammals, and also contain a large number of me?tabolites, which form a complex relationship between mother and newborn mammals. The application of meta?bonomic analysis in the research of breast milk can discover the changes of tiny molecular substances, and combined with bioinformatics analysis, key metabolic markers can be presented, as well the action mechanism of the nutrients on milk metabolism spectrum can be predicted. This paper summarized the literature on the ap?plication of metabonomics in human milk and bovine milk analysis, and combined with the other milk or metabolomics research, described the variation and effect factors of some low abundance differential metabo?lites in breast milk, and analyzed the potential research direction of breast milk in the future, in order to pro?vide new ideas for revealing the physiological mechanism of milk metabolites.[ Chinese Journal of Animal Nu?trition, 2019, 31(9) :4000?4007]关键词
代谢组学/人乳汁/牛乳汁/差异代谢物/生物标志物Key words
metabolomics/human milk/bovine milk/differential metabolites/biomarkers分类
农业科技引用本文复制引用
付力立,江婧,陶金忠,曹随忠..基于代谢组学的乳汁中代谢物研究进展[J].动物营养学报,2019,31(9):4000-4007,8.基金项目
国家自然科学基金地区科学基金项目(31660731) （31660731）
四川农业大学学科建设双支计划(03571537) （03571537）
