动物营养学报2019，Vol.31Issue(10)：4701-4709,9.DOI:10.3969／j.issn.1006⁃267x.2019.10.035
黑沙蒿多糖对大鼠生长性能及抗氧化功能的影响
Effects of Artemisia ordosica Polysaccharide on Growth Performance and Antioxidant Function of Rats
摘要
Abstract
This experiment was conducted to investigate the effects of Artemisia ordosica polysaccharide ( AOP) on growth performance and antioxidant function of rats. A total of 12 Wistar rats were randomly divid?ed into 2 groups with 6 rats per group. The rats in control group were fed a basal diet, and those in AOP group were fed a diet supplemented with 0.03% AOP on the basis of basal diet. The experiment period was 21 days. The results showed as follows: compared with the control group, 1) diet supplemented with 0.03% AOP sig?nificantly increased the average daily gain ( ADG) and the ratio of gain to feed ( G／F) ( P＜0.05 or P＜0.01) , and there was no significant effect on the average daily intake ( ADFI) of rats ( P＞0.05) ; 2) diet supplemen?ted with 0.03% AOP significantly increased serum triglycerides ( TG) , calcium ( Ca) and phosphorus ( P) contents ( P＜0.05) , but significantly decreased serum alkaline phosphatase ( ALP) activity and the contents of urea (UREA) and creatinine ( CRE) of rats ( P＜0.05 or P＜0.01) ; 3) diet supplemented with 0.03%AOP significantly improved the activities of catalase ( CAT) and glutathion peroxidase ( GPx) and the expression levels of superoxide dismutase ( SOD) 1 and SOD2 genes in liver, the activities of SOD and GPx and the ex?pression levels of CAT, GPx1, SOD1 and SOD2 genes in spleen, total antioxidant capacity ( T?AOC) and SOD2 gene expression level in kidney of rats ( P＜0.05 or P＜0.01). In conclusion, diet supplemented with 0.03% AOP can promote the growth and antioxidant function of rats, and it is hopeful to be used as a natural plant source feed additive in animal diet.[ Chinese Journal of Animal Nutrition, 2019, 31(10) :4701?4709]关键词
黑沙蒿多糖/大鼠/血清生化指标/抗氧化/基因表达Key words
Artemisia ordosica polysaccharide/rats/serum biochemical indices/antioxidant/gene expression分类
农业科技引用本文复制引用
邢媛媛,郭世伟,石璐璐,徐元庆,金晓,红雷,史彬林..黑沙蒿多糖对大鼠生长性能及抗氧化功能的影响[J].动物营养学报,2019,31(10):4701-4709,9.基金项目
研究生科研创新资助项目( B2018111947) （ B2018111947）
