临床神经病学杂志2019，Vol.32Issue(5)：383-386,4.
CSF外泌体在CNS疾病诊断与应用价值的研究进展
Research progress on diagnosis and application value of CSF exosome in CNS disease
摘要
Abstract
Exosomes are vesicles released into extracellular cells by fusion of intracellular polyvesicles and cell membranes. Exosomes are secreted by a variety of cells and exist in a variety of body fluids. Exosomes contain proteins, lipids and nucleic acids, which can participate in the information exchange between cells. Exosomes secreted by CNS cells are involved in the occurrence and development of CNS diseases. Recent studies have shown that exosomes can not only serve as early diagnostic markers for CNS diseases, but also have therapeutic potential for CNS diseases. In this paper, the development, diagnosis and treatment of CSF exosomes in CNS diseases were reviewed.关键词
外泌体/CNS疾病/诊断标志物/发病机制Key words
exosomes/CNS diseases/diagnostic markers/pathogenic mechanisms分类
医药卫生引用本文复制引用
葛小旭,季秋虹..CSF外泌体在CNS疾病诊断与应用价值的研究进展[J].临床神经病学杂志,2019,32(5):383-386,4.基金项目
国家自然科学基金(81201016) （81201016）
江苏省"六大人才高峰"高层次人才培养资助项目( WSN-094) （ WSN-094）
南通市民生示范推广项目(MS32015026 ) （MS32015026 ）
