中国卒中杂志2019，Vol.14Issue(8)：745-749,5.DOI:10.3969/j.issn.1673-5765.2019.08.002
数据库匹配方法提高卒中队列死亡结局准确性的研究
Improve the Accuracy of Patients Death Outcome in Stroke Cohort Study by Database Matching
摘要
Abstract
Objective To explore the data matching profile between stroke cohort in large multicenter study and the administrative data, and to provide new ideas and methods for data quality control in similar clinical studies. Methods The data of 12 112 inpatients with ischemic stroke who completed the 90-day follow-up from multicenter clinical trial from 2015 to 2017 were selected. The selected data were matched with all the deaths in the China National Disease Surveillance Points System from 2015 to 2017. The differences in regional and hospital distribution and patients characteristics were compared and analyzed between the group of unmatched patients with no death information in stroke cohort study while who had died as shown in China National Disease Surveillance Points System and the group of matched patients with the same death information in the two data. Results There were no statistically significant differences in regional and hospital distribution and patients characteristics between the two groups. However, according to the data trend, the unmatched rate of death information in the patients with NIHSS ≤3 on admission was higher than that in the patients with NIHSS >3 on admission (11.36% vs 6.56%), and the unmatched rate of death information in the patients living alone was higher than that in the patients living with family (13.16% vs 7.65%). Conclusions It is more difficult to obtain accurate death outcome information in patients with relatively mild neurologic impairment and patients living alone after discharge. The database matching method can make up for the lack of follow-up information in large multicenter cohort studies, which can provide accurate death outcome information of patients for stroke cohort studies.关键词
数据库匹配/卒中队列/死亡Key words
Database matching/Stroke cohort study/Death引用本文复制引用
吕微,姜勇,孟霞,黄馨莹,周脉耕..数据库匹配方法提高卒中队列死亡结局准确性的研究[J].中国卒中杂志,2019,14(8):745-749,5.基金项目
北京市科技计划项目(D151100002015003)国家重点研发计划资助(2018YFC1311700, 2018YFC1311706) （D151100002015003）
