化工学报2019，Vol.70Issue(10)：3859-3868,10.DOI:10.11949/0438-1157.20190536
连续微反应加氢技术在有机合成中的研究进展
Research progress of continuous hydrogenation in organic synthesis
摘要
Abstract
The hydrogenation reaction is a type of reaction which is very common in organic synthesis. The conventional batch hydrogenation reactor has the problems of low reaction efficiency, cumbersome operation and poor safety. The method of heterogeneous hydrogenation in a continuous microreactor can provide higher mass transfer performance, easy recycling of the catalyst and the purification of the product are more convenient, which can greatly improve the production efficiency and reduce the loss of precious metal catalysts. With these advantages, continuous hydrogenation technology in microreactors has received more and more attention. The research progress of commonly used microreactors and solid metal catalyst types, as well as heterogeneous high-efficiency catalytic hydrogenation of different functional groups in continuous microreactor are described in this paper. On this basis, the application of this technology in the field of fine chemicals is prospected. The continuous microreactor technology enables the hydrogenation process under safer, more efficient and more environmentally friendly conditions. It has high industrial application value and is one of the key development directions in the chemical industry in the future.关键词
连续流/催化加氢/微反应器/选择性加氢/非均相反应Key words
continuous flow/catalytic hydrogenation/microreactor/selective hydrogenation/heterogeneous reaction分类
化学化工引用本文复制引用
屠佳成,桑乐,艾宁,徐建鸿,张吉松..连续微反应加氢技术在有机合成中的研究进展[J].化工学报,2019,70(10):3859-3868,10.基金项目
国家自然科学基金项目(21506110) （21506110）
化学工程联合国家重点实验室自主课题(SKL-ChE-17T01 ) （SKL-ChE-17T01 ）
