中风与神经疾病杂志2019，Vol.36Issue(10)：910-914,5.
老年脑小血管病影像学总负担评分与认知功能障碍的相关性分析
The correlation analysis of the total neuroimaging burden score and cognitive dysfunction in elderly patients with cerebral small vascular disease
矣方圆 1邢艳晖 1王瑞萍1
作者信息
- 1. 辽宁省金秋医院神经内科,辽宁 沈阳110016
- 折叠
摘要
Abstract
Objective To study the relationship between total neuroimaging burden score and cognitive dysfunction in elderly patients with cerebral small vascular disease (CSVD). Methods There was included 319 patients ( aged ≥65 years) which were admitted to the outpatient or inpatient department of Jinqiu Hospital of Liaoning Province and wew diag-nosed with CSVD,from June 2016 to May 2019. The total burden of CSVD was used to evaluate the four neuroimaging fea-tures that included asymptomatic lacunar infarction,white matter hyperintensity,cerebral microbleeds and enlarged perivas-cular space. The patients were divided into the mild group (0 points) with 145 cases,the moderate group (1~2 points) with 131 cases and the severe group (3~4 points) with 43 cases. Mini-mental status inventory (MMSE) and Montreal cog-nitive assessment scale (MoCA) were used to assess the cognitive ability of the patients and the data of three groups were statistically analyzed. Results The total burden score was positively correlated with age of the severe group (r=0. 841,P=0. 035<0. 05). The memory score of severe group was lower than those of the mild group (P=0. 029),and the recall a-bility score of moderate and severe groups were lower than those of the mild group (P=0. 036) in the MMSE score. The memory and language ability score of the severe group was lower than those of the mild group (P=0. 031,0. 029),and the visual space and executive ability and delayed recall score of moderate and severe groups were lower than those of the mild group (P=0. 036,0. 014) in the MoCA score. Conclusion The total CSVD burden score is an effective imaging evalua-tion method for whole brain damage and associated with decreased overall cognitive function,may be a predictor of cognitive dysfunction. Combined and accumulating presence of the four neuroimaging features in CSVD were more serious performance to visual space and executive,memory,recall ability and language ability.关键词
老年人/ 脑小血管病/ 影像学总负担评分/ 认知功能障碍Key words
Elderly/ Cerebral small vascular disease/ Total neuroimaging burden score/ Cognitive dysfunction分类
医药卫生引用本文复制引用
矣方圆,邢艳晖,王瑞萍..老年脑小血管病影像学总负担评分与认知功能障碍的相关性分析[J].中风与神经疾病杂志,2019,36(10):910-914,5.
