数字中医药(英文)2018,Vol.1Issue(4):316-330,15.
白木香化学成分及其药理作用与质量控制的研究进展
Advance in Studies on Chemical Constituents, Pharmacology and Quality Control of Aquilaria sinensis
摘要
Abstract
Aquilaria sinensis (Thymelaeaceae) is widely cultivated in southern China for its significant medicinal usage. The resinous wood, the most used part of the plant as traditional Chinese medicine (TCM), locally called "Chen Xiang (沉香)" or Chinese agarwood, has been traditionally used for the treatment of circulatory disorders, abdominal pain, vomiting, and dyspnea. Till date, over 249 compounds have been isolated and identified from this plant. A range of bioactivities, including α-glucosidase inhibitory effects, anti-inflammatory, cytotoxicity, neuroprotective, anti-neuroinflammatory, antimicrobial and acetylcholinesterase inhibitory effects, along with some of the pharmacological mechanisms have been reported for the pure compounds or extracts of Aquilaria sinensis. For the purpose of quality control and clinical safety of drug usage, modern analytical instruments and chemical analysis methods have been applied for analyses of Aquilaria sinensis. In order to comprehensively understand the medicinal application and to fully utilize the plant, a literature search on the herb based on databases including SciFinder, Web of Science, Pubmed, Google Scholar and others was performed and the information regarding to the phytochemistry investigations, pharmacological studies and quality control was summarized in this paper.关键词
白木香/瑞香科/植物化学/药理作用/质量控制Key words
Aquilaria sinensis/Thymelaeaceae/Phytochemistry/Pharmacological activity/Quality control引用本文复制引用
袁汉文,赵建平,刘永蓓,邱伊星,谢青玲,李明姣,Ikhlas A. KHAN,王炜..白木香化学成分及其药理作用与质量控制的研究进展[J].数字中医药(英文),2018,1(4):316-330,15.基金项目
We thank for the funding support from the Administration of Traditional Chinese Medicine of Hunan Province (201673), Hunan Province Universities 2011 Collaborative Innovation Center of Protection and Utilization of Hu-xiang Chinese Medicine Resources (HXZY-2015-005 and HXZY-2015-012), the State Key Subject of TCM Diagnostics in Hunan University of Chinese Medicine (2015ZYZD06), and Hunan Provincial KeyLaboratory of Dong Medicine (2015TP1020-02). (201673)