肿瘤预防与治疗2019，Vol.32Issue(11)：993-997,5.DOI:10.3969/j.issn.1674-0904.2019.11.008
2011~2018年四川省遂宁市农村人群早期食管癌内镜筛查分析
Analysis on Endoscopic Screening for Early Esophageal Cancer in Rural Population in Suining,Sichuan Province,2011-2018
摘要
Abstract
Objective:To analyze the value of endoscopy in the diagnosis of esophageal cancer, and explore the risk fac-tors of esophageal cancer. Methods:A total of 14,439 subjects, 40-69 year olds in the rural areas of Anju district in She-hong Town in Suining, who received painless endoscopy in our hospital from July 2011 to June 2018 were studied. The sensi-tivity, specificity and negative and positive predictive value of painless endoscopy in the diagnosis of esophageal cancer were analyzed with pathological results as the gold standard. Results of endoscopic screening were analyzed. Risk factors of esoph- ageal cancer were analyzed by univariate and multivariate logistic regression analysis. Results:Among the 14, 439 subjects screened, 199 cases of high-grade dysplasia of the e-sophagus were found by endoscopy, with a detection rate of 1. 38% , including 173 cases of early esophageal cancer with a diagnosis rate of 87% . The sensitivity was 96. 34% (184／191) for endoscopic screening, and the specificity of endoscopic screening was 99. 9% (14,233／14,248). The detection rate of esophageal cancer decreased year by year, and the detection rate in males was higher than that in females. Difference was statistically significant except in 2015 (P<0. 05). Univariate and multivariate logistic regression analysis suggested that male, over 55 years old, smoking, drinking and poor dietary habits were risk factors for esophageal cancer (P<0. 05). Conclusion:Based on survey results, endoscopy can improve the effect of screening test for early esophageal cancer, which helps to prevent the occurrence of esophageal cancer, for elderly male people with poor dietary habits or history of smoking or drinking.关键词
食管癌/内窥镜/筛查/发病趋势/危险因素Key words
Esophageal cancer/Endoscopy/Screening/Morbidity trends/Risk factors分类
医药卫生引用本文复制引用
杨彬,龙晓奇,荆晓娟,陈袁..2011~2018年四川省遂宁市农村人群早期食管癌内镜筛查分析[J].肿瘤预防与治疗,2019,32(11):993-997,5.基金项目
国家重点研发计划项目(编号:2016YFC1302800、2016YFC0901400) This study was supported by National Key R&D Program of China(NO.2016YFC1302800,NO.2016YFC0901400) . （编号:2016YFC1302800、2016YFC0901400）
