临床神经外科杂志2019，Vol.16Issue(6)：465-471,7.DOI:10.3969/j.issn.1672-7770.2019.06.002
低级别胶质瘤及混合神经元胶质瘤相关癫痫的手术治疗策略
Surgical strategy for low-grade glioma and mixed neuron glioma-related epilepsy
摘要
Abstract
Objective To explore the surgical strategies for low-grade glioma and mixed neuron glioma-related epilepsy.Methods The clinical data of 171 patients with low-grade glioma and mixed neuronal glioma-related epilepsy who underwent surgery from 2011 to 2017 in Department of Epilepsy Surgery , Guangdong Sanjiu Brain Hospital were analyzed retrospectively.And the related literatures were reviewed.Results 169 patients underwent non-invasive stage I assessment and obtained resections under the intraoperative cortical electrode monitoring.2 patients underwent SEEG monitoring to determine the extent of epileptogenic zone and then received craniotomy. Patients with neoplastic lesions involving the functional area underwent surgery with intraoperative awakening.32 cases were lesion subtotal resection , and only 6 were lesion total resection.The remaining patients had a larger resection range than the tumor lesions.All patients had no surgical complications such as neurological dysfunction , intracranial infection, and hematoma.Every patient took anti-epileptic drugs after surgery.After 1 to 7 years of follow-up, 149 patients obtained EngleⅠlevel, 19 obtained Engle Ⅱ level, 1 obtained Engle Ⅲ level, 2 obtained Engle Ⅳ level. Conclusions Surgical treatment of low-grade glioma and neuronal mixed glioma-related epilepsy is an important part of epilepsy surgery.It should be evaluated reasonably according to the preoperative evaluation procedure of epilepsy surgery , and individualized surgical strategy can improve the patients’prognosis and quality of life according to the specific situation.关键词
低级别胶质瘤/神经元混合胶质瘤/术中皮层电极监测/SEEG监测Key words
low-grade glioma/mixed neuron glioma/intraoperative cortical electrode monitoring/SEEG monitoring分类
医药卫生引用本文复制引用
华刚,谭红平,张立民,李少春,陈俊喜,朱丹..低级别胶质瘤及混合神经元胶质瘤相关癫痫的手术治疗策略[J].临床神经外科杂志,2019,16(6):465-471,7.基金项目
广东省医学科研基金(B2018169) （B2018169）
