临床神经外科杂志2019，Vol.16Issue(6)：507-512,6.DOI:10.3969/j.issn.1672-7770.2019.06.010
后交通动脉瘤破裂的临床及形态学危险因素分析
Clinical and morphological risk factors of posterior communicating aneurysm rupture
摘要
Abstract
Objective To provide clinical interventions by studying the clinical and morphological risks of the posterior communicating aneurysm rupture.Methods Patients with posterior communicating artery aneurysm, hospitalized in the Affiliated Hospital of Xuzhou Medical University, were analyzed retrospectively.All cases were divided into two groups, i.e.the unruptured aneurysm group and the ruptured aneurysm group.The morphological and clinical features of each group were analyzed as well as their relationships with the danger of rupture. Furthermore, the unruptured group was divided into oculomotor nerve paralysis and without oculomotor nerve paralysis to compare the clinical and morphological characteristics and to detect the distinctions if any.Results In the ruptured and unruptured groups, univariate analysis showed that there were significant differences in hypertension ( χ2 ＝4.174,P＝0.04) , aneurysm height／neck ( aspect AR)≥1.5 ( χ2 ＝8.575, P＝0.003) , and the apex of the aneurysm points to the posterior-inferior-lateral ( χ2 ＝17.435, P ＝0.01 ).Multivariate analysis showed that hypertension ( OR＝3.443, P＝0.004) 、AR≥1.5 ( OR＝1.011, P＝0.047) and the apex of the aneurysm pointing to the posterior and inferior ( OR＝5.704, P＝0.016) were independent risks of the rupture of the posterior communicating aneurysm.In the unruptured group, the univariate analysis showed that the( t＝9.433, P＝0.00) and the apex of the aneurysm directed to posterior-inferior-lateral ( χ2 ＝24.840, P＝0.00 ) were significantly higher than those of the control group.Conclusions The ratio of AR≥1.5, history of hypertension and the apical direction of posterior communicating artery aneurysm( PCoAA) are the risk factors of the rupture of posterior communicating artery aneurysm.The high AR of PCoAA with oculomotor nerve paralysis and the apex of the aneurysm points to the posterior-inferior-lateral may contribute to the rupture.关键词
后交通动脉瘤/动脉瘤破裂/危险因素/形态学特征/临床特征Key words
posterior communicating aneurysm/aneurysm rupture/risk factors/morphological features/clinical features分类
医药卫生引用本文复制引用
邱大志,王宇生,谢满意,朱凯强,韩凯,李中林..后交通动脉瘤破裂的临床及形态学危险因素分析[J].临床神经外科杂志,2019,16(6):507-512,6.基金项目
国家自然科学基金青年基金(81402074) （81402074）
