广西科学2019，Vol.26Issue(5)：497-502,510,7.DOI:10.13656/j.cnki.gxkx.20191106.003
十味参归灌肠液的质量标准研究
Study on Quality Standard of Shiweishengui Filling and Intesti-nal Juice
摘要
Abstract
This article is to establish the quality standard of Shiweishengui filling and intestinal juice. Thin layer chromatography(TCL)was used to qualitatively identify rhizoma Corydalis，Salvia miltiorrhiza，peach kernel and Radix Paeoniae Rubra in the preparation. The content of Dan phenolic acid B in the preparation was determined by high performance liquid chromatography(HPLC).The results showed that the TLC identification methods for the above four herbs were established and the chromatogram was characterized by clear and concentrated spots. The established method for the determination of Dan phenolic acid B content had high specificity and repeatability. When the injection amount of Dan phenolic acid B reference substance was 54. 55-545. 50μg，it had a good linear relationship with the peak area. The recovery rate of Dan phenolic acid B was 102.77%，RSD=1.01%.The qualitative and quantitative method established in this paper can effectively control the quality of the traditional Chinese medicine preparation “Shiweishengui filling and intestinal juice.关键词
十味参归灌肠液/质量标准/丹酚酸B/延胡索/丹参/桃仁/赤芍/TLC/HPLCKey words
Shiweishengui filling and intestinal juice/quality standard/Dan phenolic acid B/ rhizoma Coryda1is/Salvia miltiorrhiza/peach kernel/Radix Paeoniae Rubra/TLC/HPLC分类
医药卫生引用本文复制引用
何艳春1,莫秋瑜1,黄瑞松2..十味参归灌肠液的质量标准研究[J].广西科学,2019,26(5):497-502,510,7.基金项目
广西壮族自治区卫生厅中医药医院制剂类课题(No:GZYZ1120)资助. （No:GZYZ1120）
