广西科学2019，Vol.26Issue(5)：527-531,538,6.DOI:10.13656/j.cnki.gxkx.20191106.001
ICP-MS分析复方甘草口服溶液中15种元素
Analysis of 15 Elements in Compound Licorice Oral Solution by ICP-MS
摘要
Abstract
An inductively coupled plasma mass spectrometry(ICP-MS) method was established to determine 15 elements(Cr，Mn，Co，Ni，Cu，Zn，As，Cd，Sn，Sb，Ba，Hg，Pb，A1，Fe)in compound licorice oral solution. The compound licorice oral solution sample was digested by microwave，the corresponding element was selected as an internal standard according to the mass of the element to be tested，and the collision mode(helium mode) was used for measurement. The result showed that the linear relationship of the detected 15 element was good，and the correlation coefficients were all greater than 0.999. The detection limit of each element was between 0.08 ng·mL-1 and 38.00 ng·mL-1，and the recovery rate was between 88. 57%and 107.10 %(n=6).The method has the advantages of simple operation，high analysis speed，high sensitivity， wide linear range，and simultaneous determination of various elements，and is suitable for the determination of elements in the compound licorice oral solution.关键词
复方甘草口服溶液/电感耦合等离子体质谱/元素/微波消解/重金属/限量Key words
compound licorice oral solution/ICP-MS/element/microwave digestion/heavy metal/limit分类
医药卫生引用本文复制引用
李智明,邓鸣,卢日刚..ICP-MS分析复方甘草口服溶液中15种元素[J].广西科学,2019,26(5):527-531,538,6.基金项目
广西壮族自治区药品监督管理局 2019 年广西药品安全科学技术研究项目(桂药科 2019-(直属))资助. （桂药科 2019-(直属）
