肿瘤预防与治疗2019，Vol.32Issue(12)：1135-1139,5.DOI:10. 3969／j. issn. 1674-0904. 2019. 12. 012
LncRNAs在甲状腺癌中的生物学功能及其临床价值研究进展*
Progress in Biological Functions and Clinical Significance of Long Non-Coding RNAs in Thyroid Cancer
摘要
Abstract
Thyroid cancer is one of the most common endocrine cancers with rapidly increasing incidence in recent dec-ades. Although the majority of patients with thyroid cancer have a good prognosis, there is still a risk that some cases may develop into more aggressive and lethal thyroid cancers. Long noncoding RNAs (lncRNAs) have recently been demonstrated to participate in cancer progression. However, their role and molecular mechanism in thyroid cancer remain unclear. In this review, we summarize the latest findings regarding the functions and mechanism of lncRNAs in thyroid cancer, and discuss their potential clinical significance in diagnosis, prognostic biomarkers and therapeutic targets of thyroid cancer.关键词
甲状腺癌/长链非编码RNA/生物标志物Key words
Thyroid cancer/Long non-coding RNA/Biomarker分类
医药卫生引用本文复制引用
唐平,盛健峰,党好..LncRNAs在甲状腺癌中的生物学功能及其临床价值研究进展*[J].肿瘤预防与治疗,2019,32(12):1135-1139,5.基金项目
四川省卫生健康委普及应用项目(编号:19PJ052) This study was supported by grants from Health Commission of Sichuan Province (NO. 19PJ052) . （编号:19PJ052）
