中国真菌学杂志2019，Vol.14Issue(6)：338-341,373,5.
北京医院侵袭性酵母菌的感染分布及耐药性分析
Analysis of infection distribution and drug resistance of invasive yeast in Beij ing Hospital
高振祥1 1陶凤蓉2 2骈亚亚1 1聂晶晶1 1郭莉娜3 3徐英春3 3胡云建22
作者信息
- 1. 北京医院 国家老年医学中心 国家卫生健康委临床检验中心 中国医学科学院老年医学研究院,北京100730
- 2. 北京医院 检验科 国家老年医学中心 中国医学科学院老年医学研究院,北京 100730
- 3. 中国医学科学院北京协和医院检验科 侵袭性真菌病机制研究与精准诊断北京市重点实验室(BZ0447),北京100730
- 折叠
摘要
Abstract
Objective To investigate the infection distribution and to analysis drug sensitivity of invasive yeast in Beijing Hospital from 2012-2013 and 2016-2017. Methods The strains were collected for the clinical detection of invasive yeast. The strain identification and MIC detection were carried out using Komajia chromogenic medium and API20C AUX and VITEK-2 Compact YST card. All strains were also identified by mass spectrometry. Results A total of 62 invasive yeasts were detected in our hospital from 2012-2013，including 36 strains of Candida albicans, accounting for 58.06%;17 strains of Candida glabrata，accounting for 27.41%;5 strains of Candida parapsilosis, accounting for 8.06%;3 strains of Candida tropicalis, accounting for 4.83%;and 1 strain of other Candida，accounting for 1. 60%. In 2016-2017, 43 strains of invasive yeast were detected in our hospital，including 21 strains of Candida albicans, accounting for 48.83%;11 strains of Candida glabrata, accounting for 25.58%;6 strains of Candida parapsilosis，accounting for 13.95%;5strains of Candida tropicalis,accounting for 11.63%. The fungal drug-sensitive results showed that 5-fluorocytosine had different degrees of resistance to Candida albicans, Candida glabrata and Candida tropicalis. Conclusion Candida albicans plays a leading role in invasive yeast infection in our hospital. Although the drug resistance of invasive yeast in our hospital has improved in recent years, further research on fungal drug sensitivity needs to be done.关键词
侵袭性/酵母菌/念珠菌/流行病学Key words
invasive/ yeast/Candida/epidemiology分类
医药卫生引用本文复制引用
高振祥1,陶凤蓉2,骈亚亚1,聂晶晶1,郭莉娜3,徐英春3,胡云建2..北京医院侵袭性酵母菌的感染分布及耐药性分析[J].中国真菌学杂志,2019,14(6):338-341,373,5.
