中国卒中杂志2019，Vol.14Issue(11)：1101-1105,5.DOI:10.3969/j.issn.1673-5765.2019.11.005
不同严重程度缺血性卒中患者静脉溶栓后失语改善情况分析
Analysis of Aphasia Improvement after Intravenous Thrombolysis in Stroke Patients with Different Severity
摘要
Abstract
Objective To investigate aphasia improvement after intravenous thrombosis in acute ischemic stroke patients with different severity. Methods Data of 360 acute ischemic stroke patients treated with rt-PA intravenous thrombolysis in Department of Neurology, Zhengzhou People’s Hospital from April 2015 to March 2017 were collected. Based on the NIHSS score on admission, all patients were divided into two groups:NIHSS≤8 group and NIHSS>8 group. The baseline data included age, sex, hypertension, diabetes, heart disease, smoking and drinking, low density lipoprotein cholesterol, onset-to-needle time and etc. Improvement of aphasia and neurological function between the two groups were compared. Results Finally, 158 patients with aphasia were included in this study, with 49 patients with NIHSS ≤8 and 109 patients with NIHSS >8. Baseline data and neurological function improvement at 24 h after thrombolysis between the two groups had no statistical difference. The improvement percentage of aphasia at 24 h after thrombolysis in NIHSS ≤8 group was higher than that in NIHSS >8 group (67.3% vs 45.9%, P=0.021). The complete improvement percentage of aphasia at 24 h after thrombolysis in NIHSS≤8 group was higher than that in NIHSS>8 group (69.7% vs 44.0%, P=0.021). Conclusions For acute ischemic stroke patients with aphasia, the improvement percentage of aphasia in patients with NIHSS ≤8 was higher than that in patients with NIHSS >8 at 24 h after intravenous thrombolysis.关键词
失语/急性缺血性卒中/静脉溶栓Key words
Aphasia/Acute ischemic stroke/Intravenous thrombolysis引用本文复制引用
付胜奇,石宝洋,张津,宋良,张洪涛,张淑玲..不同严重程度缺血性卒中患者静脉溶栓后失语改善情况分析[J].中国卒中杂志,2019,14(11):1101-1105,5.基金项目
河南省医学科技攻关计划项目(2018020821)河南省医学科技攻关计划项目(省部共建) (SB201903028) （2018020821）
