摘要
Abstract
The spectrum of age-related cerebral small vessel diseases (ArCSVDS) is defined as a group of cerebral small vessel disease (CSVD) in which cerebral small arteries, arterioles, capillaries, venules, small veins appear ageing with age, and CSVD include deep perforating arteriopathy (DPA), β-amyloid (Aβ) related cerebral amyloid angiopathy (CAA). In the past, DPA and CAA were considered to be independent disease, while recent studies have found that they both belong to the ArCSVDS from the perspective of not only similar vascular risk factors and potential interactions, but also the mechanism. The blood brain barrier (BBB) damage, endothelial cell injury and perivascular Aβ are the common mechanism of DPA and CAA, and 30%-68% patients had both diseases.关键词
脑小血管病/增龄相关性脑小血管病谱系/深穿支动脉病/脑淀粉样血管病.Key words
Cerebral small vessel disease/Spectrum of age-related cerebral small vessel disease/Deep perforating arteriopathy/Cerebral amyloid angiopathy
